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Table 2 Cox regression analysis on overall survival and disease-free survival on CC0 patients

From: Cytoreduction plus hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis in colorectal cancer patients: a single-center cohort study

Variables

OS

DFS

Univariate

Multivariate

Univariate

Multivariate

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

Age

1.01 (0.96–1.05)

0.737

  

1.00 (0.97–1.04)

0.705

  

Sex (F)

0.77 (0.31–1.83)

0.764

  

1.20 (0.56–2.56)

0.638

  

Right colon cancer

2.51 (0.99–6.31)

0.051

  

2.37 (1.08–5.23)

0.032

  

PCI > 6

3.57 (1.43–8.92)

0.007

4.48 (1.68–11.9)

0.003

2.87 (1.27–6.45)

0.011

  

Syncronous carcinomatosis

0.82 (0.34–1.96)

0.652

  

0.71 (0.33–1.51)

0.380

  

Preoperative chemotherapy

1.49 (0.57–3.88)

0.415

  

1.45 (0.63–3.34)

0.377

  

Postoperative chemotherapy

1.59 (0.37–6.88)

0.530

  

2.71 (0.64–11.5)

0.176

  

Syncronous HIPEC

0.50 (0.15–1.70)

0.270

  

0.49 (0.18–1.28)

0.149

  

Postoperative complications Clavien-Dindo > 2

0.33 (0.44–2.45)

0.279

  

0.48 (0.11–2.04)

0.325

  

Tumor grade

        

 2

1.07 (0.14–8.30)

0.947

  

1.89 (0.25–14.4)

0.534

  

 3

1.21 (0.15–9.50)

0.854

  

2.23 (0.29–16.9)

0.440

  

T4 stage

1.13 (0.46–2.76)

0.796

  

1.04 (0.48–2.26)

0.916

  

N stage

        

 1

6.43 (1.25–33.0)

0.026

  

1.63 (0.49–5.33)

0.421

  

 2

8.23 (1.86–36.4)

0.005

3.89 (1.50–10.1)

0.005

3.05 (1.78–7.88)

0.022

2.44 (1.11–5.36)

0.027