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Table 2 Association of clinical and pathological variables with survival (cancer-specific survival)

From: Surgical resection of the primary tumor leads to prolonged survival in metastatic pancreatic neuroendocrine carcinoma

Variable

Group

N

Median (minimum–maximum) (month)

95% CI

p

All

 

350

8 (1–138)

6.769–9.231

 

Sex

    

0.309

Female

145

9 (1–112)

7.605–10.395

 

Male

205

8 (1–138)

5.891–10.109

 

Race

    

0.866

White

278

9 (1–138)

7.411–10.589

 

Black

40

7 (1–36)

5.327–8.673

 

Other

32

8 (1–92)

2.824–13.176

 

Age

    

0.012

< 65y

191

9 (1–138)

7.592–10.408

 

≥ 65y

159

6 (1–106)

4.208–7.792

 

Grade

    

0.177

III

236

9 (1–138)

7.446–10.554

 

IV

114

8 (1–76)

6.462–9.538

 

Tumor size

    

0.24

< 2 cm

4

2 (2–28)

Undefined*

 

2–4 cm

96

9 (1–92)

6.880–11.120

 

> 4 cm

152

9 (1–138)

7.346–10.654

 

Tumor location

    

0.007

Head

146

8 (1–68)

6.399–9.601

 

Overlapping

31

9 (1–112)

7.121–10.879

 

Body

28

9 (1–106)

2.912–15.088

 

Tail

80

11 (1–138)

7.952–14.048

 

Lymph node metastases

    

0.729

No

14

9 (1–60)

0.000–37.636

 

Yes

46

11 (1–138)

7.032–14.968

 

Chemotherapy

    

0.007

No

129

4 (1–138)

2.763–5.237

 

Yes

221

10 (1–112)

8.841–11.159

 

Year of diagnosis

    

0.087

< 2010

212

8 (1–138)

6.698–9.302

 

≥ 2010

138

10 (1–50)

7.705–12.295

 

Primary site surgery

    

< 0.001

Surgery performed

50

12 (1–138)

2.079–21.921

 

Surgery not performed

300

8 (1–112)

6.594–9.406

 

Recommended but not performed

38

9 (1–76)

6.123–11.877

 

Not recommended and not performed

262

7 (1–112)

5.523–8.477

 

Site specific surgery

    

0.39

Local or partial pancreatectomy

24

26 (2–50)

11.541–40.459

 

Total pancreatectomy

4

8 (4–138)

0.000–95.547

 

Whipple

19

11 (1–68)

8.525–13.475

 

Unknown

3

9 (4–26)

0.998–17.002

 

Primary site surgery

    

0.216

Primary site only

25

10 (3–68)

3.129–16.871

 

Primary site and distant site

25

19 (1–138)

1.487–36.513

 

Distant site only

10

8 (1–112)

4.901–11.099

 
  1. *Too small sample size and too different survival data of the patients might lead to the undefinition of the corresponding 95% CI
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World Journal of Surgical Oncology

ISSN: 1477-7819

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