Table 3 Cox-regression model of disease-free survival (DFS) in rectum cancer
From: Tumor budding for predicting prognosis of resected rectum cancer after neoadjuvant treatment
n | Median DFS (months) | Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |||||
Lower | Upper | Lower | Upper | |||||||
Gender | Female (n = 24) | 28 | 0.69 | 0.35 | 1.36 | 0.29 | ||||
Male (n = 51) | 31 | |||||||||
Grade | Poorly (n = 20) | 22 | 2.74 | 1.45 | 5.19 | 0.00 | 3,37 | 1,75 | 6.49 | 0.00 |
Well-intermediate (n = 55) | 32 | |||||||||
Stage | Stage 1–2 (n = 39) | 38 | 2.54 | 1.31 | 4.90 | 0.00 | ||||
Stage 3 (n = 36) | 28 | |||||||||
Lymph nodes | N 0 (n = 39) | 42 | 2.37 | 1.22 | 4.59 | 0.01 | ||||
N 1–2 (n = 36) | 28 | |||||||||
Kras status, n = 41 | Wild (n = 9) | 23 | 1.42 | 0.71 | 3.72 | 0.2 | ||||
Mutant (n = 32) | 24 | |||||||||
Microsatellite instability status | Low (n = 48) | 38 | 2.44 | 1.31 | 4.55 | 0.00 | ||||
High (n = 27) | 26 | |||||||||
Tumor budding | Low-intermediate (n = 29) | 43 | 2.57 | 1.18 | 5.57 | 0.01 | 3.14 | 1.42 | 6.94 | 0.00 |
High (n = 46) | 28 | |||||||||