Table 4 Multivariate analysis of clinicopathological characteristics associated with ≥ 3 ALN metastasis
Characteristics | OR | 95% CI | P value |
|---|---|---|---|
ALN metastasis identified by | 0.003 | ||
FNA | 6.98 | 1.95–25.02 | |
SLNB | 1.0 | ||
Tumor stage | 0.738 | ||
T1 | 1.0 | ||
T2 | 1.12 | 0.57–2.21 | |
Number of suspicious ALNs at US | < 0.001 | ||
≤ 1 | 1.0 | ||
> 1 | 5.38 | 2.31–12.56 | |
Thickness of the cortex at US (mm) | 0.068 | ||
≤ 3.5 | 1.0 | ||
> 3.5 | 1.81 | 0.96–3.41 | |
Histological grade | 0.233 | ||
I | 1.0 | ||
II | 0.31 | 0.03–3.36 | 0.335 |
III | 0.50 | 0.05–5.40 | 0.570 |
LVI | < 0.001 | ||
Negative | 1.0 | ||
Positive | 4.78 | 2.04–11.24 | |
Multifocality | 0.013 | ||
Unifocal | 1.0 | ||
Multifocal | 3.93 | 1.33–11.63 | |
HER2 status | 0.932 | ||
Negative | 1.0 | ||
Positive | 1.03 | 0.51–2.11 | |
Ki67 (%, mean) | 0.567 | ||
< 14% | 1.0 | ||
≥ 14% | 0.79 | 0.35–1.79 | |