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Table 5 Association between SNPs in OSMR and patient’s survival

From: The role of oncostatin M receptor gene polymorphisms in bladder cancer

SNP/genotype

NMIBC

MIBC

 

Alive/dead

HR (95% CI) a

P

Recurrence/Non-recurrence

HR (95% CI) b

P

Alive/dead

HR (95% CI) a

P

Recurrence/Non-recurrence

HR (95% CI) b

P

rs2278329

 GG

63/8

  

16/55

  

46/16

  

6/8

  

 GA

70/3

  

25/48

  

49/17

  

20/46

  

 AA

19/1

  

4/16

  

11/3

  

18/44

  

 Dominant

 

0.31 (0.09–1.06)

0.06

 

1.56 (0.0.84–2.89)

0.16

 

1.14 (0.57–2.26)

0.71

 

1.05 (0.56–1.96)

0.88

 Recessive

 

0.77 (0.10–6.10)

0.80

 

0.49 (0.17–1.39)

0.18

 

1.10 (0.31–3.94)

0.88

 

1.54 (0.60–3.97)

0.37

 Overdominant

 

0.31 (0.08–1.20)

0.09

 

2.16 (1.17–3.98)

0.01

 

1.10 (0.57–2.13)

0.78

 

0.89 (0.49–1.63)

0.71

rs2292016

 GG

66/9

  

15/60

  

48/13

  

15/46

  

 GT

66/3

  

23/46

  

47/19

  

24/42

  

 TT

20/0

  

7/13

  

11/4

  

5/10

  

 Dominant

 

0.22 (0.06–0.86)

0.029

 

1.74 (0.92–3.27)

0.08

 

1.36 (0.69–2.70)

0.38

 

1.45 (0.78–2.72)

0.24

 Recessive

 

NA (0–NA)

0.98

 

1.18 (0.51–2.71)

0.70

 

1.21 (0.43–3.52)

0.72

 

1.12 (0.36–2.88)

0.82

 Overdominant

 

0.37 (0.09–1.43)

0.15

 

1.58 (0.86–2.90)

0.14

 

1.25 (0.65–2.43)

0.50

 

1.37 (0.75–2.52)

0.30

  1. N corresponds to the number of individuals
  2. aAdjusted by age, sex, smoking status, tumor stage, and recurrence
  3. bAdjusted by age, sex, smoking status, and tumor stage. Italicized values indicate a significant difference at the 5% level