Table 1 Patient characteristics
From: Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma
| Leiomyosarcoma (n = 21) | Liposarcoma (n = 28) | p value | |
|---|---|---|---|
| Age at diagnosis | |||
| Median (range) | 57 (38–85) | 55 (39–78) | 0.93 |
| Gender, n (%) | |||
| Male | 9 (43%) | 18 (64%) | 0.16 |
| Female | 12 (57%) | 10 (36%) | |
| Race, n (%) | |||
| Non-Hispanic white | 7 (33%) | 24 (86%) | 0.001 |
| Hispanic | 1 (5%) | 0 (0%) | |
| Black | 11 (52%) | 4 (14%) | |
| Asian | 1 (5%) | 0 (0%) | |
| Unknown | 1 (5%) | 0 (0%) | |
| ECOG functional status, n (%) | |||
| 0 | 10 (48%) | 9 (32%) | 0.07 |
| 1 | 6 (29%) | 17 (61%) | |
| 2 | 2 (9%) | 0 (0%) | |
| Unknown | 3 (14%) | 2 (7%) | |
| Initial presenting symptom, n (%) | |||
| Bone/abdomen/back/flank/groin pain | 15 (71%) | 16 (57%) | 0.57 |
| Enlarging painless mass | 0 (0%) | 2 (7%) | |
| Incidental finding on imaging/examination | 1 (5%) | 4 (14%) | |
| Other | 2 (10%) | 4 (14%) | |
| Unknown | 3 (14%) | 2 (7%) | |
| Length of presenting symptoms (n = 28) | |||
| Median (range) | 1.0 (0–12) | 1.1 (0–12) | 0.57 |
| Length of presenting symptoms | |||
| ≤ 2 months | 8 (38%) | 12 (43%) | 0.93 |
| > 2 months | 4 (19%) | 4 (14%) | |
| Unknown | 9 (43%) | 12 (43%) | |
| Histologic grade, n (%) | |||
| 1 | 2 (9%) | 14 (50%) | 0.002 |
| 2 | 6 (29%) | 1 (4%) | |
| 3 | 10 (48%) | 12 (43%) | |
| Unknown | 3 (14%) | 1 (4%) | |
| Tumor size (cm) [n = 39] | |||
| Median (range) | 10.4 (3–29) | 27.3 (6–54) | 0.0001 |
| Tumor size (cm) | |||
| < 15 cm | 13 (62%) | 3 (11%) | < 0.0001 |
| ≥ 15 cm | 2 (9%) | 21 (75%) | |
| Unknown | 6 (29%) | 4 (14%) | |
| Stage, n (%) | |||
| 1 | 1 (5%) | 12 (43%) | 0.002 |
| 2 | 6 (29%) | 1 (4%) | |
| 3 | 7 (33%) | 11 (39%) | |
| 4 | 4 (19%) | 1 (4%) | |
| Unknown | 3 (14%) | 3 (11%) | |
| Resection status, n (%) | |||
| No residual disease (R0) | 11 (52%) | 12 (43%) | 0.49 |
| Microscopic disease (R1) | 4 (19%) | 11 (39%) | |
| Gross residual disease (R2) | 1 (5%) | 2 (7%) | |
| No surgery (biopsy only) | 3 (14%) | 2 (7%) | |
| Unknown | 2 (10%) | 1 (4%) | |
| Neoadjuvant or adjuvant radiation | |||
| No | 9 (43%) | 17 (60%) | 0.20 |
| Yes | 8 (38%) | 10 (36%) | |
| Unknown | 4 (19%) | 1 (4%) | |
| Recurrent disease, n (%) | |||
| No | 5 (24%) | 7 (25%) | 0.56 |
| Yes | 14 (67%) | 15 (54%) | |
| Unknown | 2 (9%) | 6 (21%) | |
| Local recurrence, n (%) | |||
| No | 12 (57%) | 7 (25%) | 0.03 |
| Yes | 4 (19%) | 14 (50%) | |
| Not applicable | 3 (14%) | 1 (4%) | |
| Unknown | 2 (10%) | 6 (21%) | |
| Resection of local recurrence, n (%) | |||
| No | 14 (67%) | 9 (32%) | 0.02 |
| Yes | 2 (10%) | 12 (43%) | |
| Unknown | 5 (24%) | 7 (25%) | |
| Cause of death, n (%) | |||
| Metastatic or recurrent sarcoma | 7 (33%) | 8 (29%) | 0.79 |
| Heart failure | 1 (5%) | 0 (0%) | |
| Still alive | 9 (43%) | 15 (53%) | |
| Unknown | 4 (19%) | 5 (18%) | |
| Alive, n (%) | |||
| Dead | 12 (57%) | 12 (44%) | 0.56 |
| Alive | 9 (43%) | 15 (56%) | |