From: Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma
 | Leiomyosarcoma (n = 21) | Liposarcoma (n = 28) | p value |
---|---|---|---|
Age at diagnosis | |||
 Median (range) | 57 (38–85) | 55 (39–78) | 0.93 |
Gender, n (%) | |||
 Male | 9 (43%) | 18 (64%) | 0.16 |
 Female | 12 (57%) | 10 (36%) | |
Race, n (%) | |||
 Non-Hispanic white | 7 (33%) | 24 (86%) | 0.001 |
 Hispanic | 1 (5%) | 0 (0%) | |
 Black | 11 (52%) | 4 (14%) | |
 Asian | 1 (5%) | 0 (0%) | |
 Unknown | 1 (5%) | 0 (0%) | |
ECOG functional status, n (%) | |||
 0 | 10 (48%) | 9 (32%) | 0.07 |
 1 | 6 (29%) | 17 (61%) | |
 2 | 2 (9%) | 0 (0%) | |
 Unknown | 3 (14%) | 2 (7%) | |
Initial presenting symptom, n (%) | |||
 Bone/abdomen/back/flank/groin pain | 15 (71%) | 16 (57%) | 0.57 |
 Enlarging painless mass | 0 (0%) | 2 (7%) | |
 Incidental finding on imaging/examination | 1 (5%) | 4 (14%) | |
 Other | 2 (10%) | 4 (14%) | |
 Unknown | 3 (14%) | 2 (7%) | |
Length of presenting symptoms (n = 28) | |||
 Median (range) | 1.0 (0–12) | 1.1 (0–12) | 0.57 |
Length of presenting symptoms | |||
 ≤ 2 months | 8 (38%) | 12 (43%) | 0.93 |
 > 2 months | 4 (19%) | 4 (14%) | |
 Unknown | 9 (43%) | 12 (43%) | |
Histologic grade, n (%) | |||
 1 | 2 (9%) | 14 (50%) | 0.002 |
 2 | 6 (29%) | 1 (4%) | |
 3 | 10 (48%) | 12 (43%) | |
 Unknown | 3 (14%) | 1 (4%) | |
Tumor size (cm) [n = 39] | |||
 Median (range) | 10.4 (3–29) | 27.3 (6–54) | 0.0001 |
Tumor size (cm) | |||
 < 15 cm | 13 (62%) | 3 (11%) | < 0.0001 |
 ≥ 15 cm | 2 (9%) | 21 (75%) | |
 Unknown | 6 (29%) | 4 (14%) | |
Stage, n (%) | |||
 1 | 1 (5%) | 12 (43%) | 0.002 |
 2 | 6 (29%) | 1 (4%) | |
 3 | 7 (33%) | 11 (39%) | |
 4 | 4 (19%) | 1 (4%) | |
 Unknown | 3 (14%) | 3 (11%) | |
Resection status, n (%) | |||
 No residual disease (R0) | 11 (52%) | 12 (43%) | 0.49 |
 Microscopic disease (R1) | 4 (19%) | 11 (39%) | |
 Gross residual disease (R2) | 1 (5%) | 2 (7%) | |
 No surgery (biopsy only) | 3 (14%) | 2 (7%) | |
 Unknown | 2 (10%) | 1 (4%) | |
Neoadjuvant or adjuvant radiation | |||
 No | 9 (43%) | 17 (60%) | 0.20 |
 Yes | 8 (38%) | 10 (36%) | |
 Unknown | 4 (19%) | 1 (4%) | |
Recurrent disease, n (%) | |||
 No | 5 (24%) | 7 (25%) | 0.56 |
 Yes | 14 (67%) | 15 (54%) | |
 Unknown | 2 (9%) | 6 (21%) | |
Local recurrence, n (%) | |||
 No | 12 (57%) | 7 (25%) | 0.03 |
 Yes | 4 (19%) | 14 (50%) | |
 Not applicable | 3 (14%) | 1 (4%) | |
 Unknown | 2 (10%) | 6 (21%) | |
Resection of local recurrence, n (%) | |||
 No | 14 (67%) | 9 (32%) | 0.02 |
 Yes | 2 (10%) | 12 (43%) | |
 Unknown | 5 (24%) | 7 (25%) | |
Cause of death, n (%) | |||
 Metastatic or recurrent sarcoma | 7 (33%) | 8 (29%) | 0.79 |
 Heart failure | 1 (5%) | 0 (0%) | |
 Still alive | 9 (43%) | 15 (53%) | |
 Unknown | 4 (19%) | 5 (18%) | |
Alive, n (%) | |||
 Dead | 12 (57%) | 12 (44%) | 0.56 |
 Alive | 9 (43%) | 15 (56%) |