Table 5 Meta-analysis of odds ratio (OR) for cancer-specific survival (CSS)
CSS | Factors | Study size | OR (95%CI, P value) | I2 (%) | |
|---|---|---|---|---|---|
2-yr | All included studies | 6 | 0.78(0.33–1.81,0.56) | 73 | |
Original tumor state | HG | 2 | 1.09(0.15–8.15,0.93) | 92 | |
G3 | 4 | 0.63(0.25–1.60,0.33) | 48 | ||
Radical cystectomy timing | > 3 months | 1 | 3.13(1.25–7.86,0.02) | not available | |
< 3 months | 4 | 0.59(0.26–1.32,0.2) | 56 | ||
Bladder preservation modality | BCG | 4 | 0.63(0.25–1.60,0.33) | 48 | |
Mix | 2 | 1.09(0.15–8.15,0.93) | 92 | ||
Age | < 65 years old | 2 | 1.12(0.52–2.41,0.77) | 0 | |
> 65 years old | 4 | 0.60(0.18–1.98,0.4) | 82 | ||
5-yr | All included studies | 9 | 0.78(0.44–1.38,0.4) | 75 | |
Original tumor state | HG | 3 | 1.37(0.40–4.67,0.62) | 84 | |
G3 | 6 | 0.59(0.30–1.16,0.13) | 70 | ||
Radical cystectomy timing | > 3 months | 2 | 0.89(.06–2.87,0.93) | 92 | |
< 3 months | 5 | 0.91(0.52–1.58,0.73) | 49 | ||
Bladder preservation modality | BCG | 5 | 0.70(0.35–1.41,0.32) | 65 | |
Mix | 4 | 0.91(0.31–2.71,0.87) | 85 | ||
Age | < 65 years old | 3 | 0.74(0.19–2.83,0.66) | 76 | |
> 65 years old | 6 | 0.78(0.39–1.55,0.47) | 77 | ||
10-yr | All included studies | 5 | 1.22(0.59–2.52,0.6) | 80 | |
Original tumor state | HG | 1 | 3.04(1.53–6.05,0.002) | not available | |
G3 | 4 | 0.96(0.45–2.03,0.91) | 76 | ||
Radical cystectomy timing | > 3 months | 1 | 3.04(1.53–6.05,0.002) | not available | |
< 3 months | 3 | 1.51(0.97–2.34,0.07) | 48 | ||
Bladder preservation modality | BCG | 4 | 0.96(0.45–2.03,0.91) | 76 | |
Mix | 1 | 3.04(1.53–6.05,0.002) | not available | ||
Age | < 65 years old | 2 | 1.22(0.35–4.24,0.75) | 70 | |
> 65 years old | 3 | 1.22(0.41–3.65,0.73) | 87 | ||
15-yr | All included studies | 3 | 2.19(1.21–3.95,0.009) | 55 | |