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Table 5 Correlation between radiological response and PFS

From: Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG0304

 

5-year PFS of CR/PR/MR (95% CI)

5-year PFS of SD/PD (95% CI)

HR (95% CI)

p value

C-index (95% CI)

RECIST

66.7% (33.7%–86.0%)

66.7% (52.9%–77.3%)

0.99 (0.34–2.92)

0.99

0.50 (0.23–0.77)

Modified RECIST

66.7% (37.5%–84.6%)

66.7% (52.4%–77.5%)

1.00 (0.37–2.70)

1.00

0.52 (0.28–0.77)

WHO

66.7% (37.5%–84.6%)

66.7% (52.4%–77.5%)

1.00 (0.37–2.70)

1.00

0.52 (0.28–0.77)

JOA

60.0% (38.4%–76.1%)

70.5% (54.6%–81.6%)

1.41 (0.62–3.21)

0.42

0.56 (0.36–0.77)

Modified Choi

59.3% (38.6%–75.0%)

71.4% (55.2%–82.6%)

1.54 (0.68–3.49)

0.30

0.61 (0.42–0.81)

  1. CR complete response, PR partial response, MR minor response, SD stable disease, PD progressive disease, HR hazard ratio