The combined effect of non-alcoholic fatty liver disease and metabolic syndrome on colorectal carcinoma mortality: a retrospective in Chinese females

Table 2 Cancer-specific mortality

Characteristics	Univariable			Multivariable
Characteristics	HR	95% CI	p value	HR	95%CI	p value
Age (years)	1.021	0.983–1.111	0.401
BMI (kg/m²)	0.932	0.821–1.120	0.212
SBP (mmHg)	1.122	0.913–1.342	0.514
DBP (mmHg)	0.932	0.821–1.104	0. 314
Triglycerides (mmol/L)	0.915	0.832–1.214	0.423
HDL (mmol/L)	1.224	1.192–1.913	0.021*	1.201	0.925–1.651	0.312
LDL (mmol/L)	1.231	1.017–1.453	0.015*	1.218	0.941–2.092	0.513
Fasting glucose (mmol/L)	1.011	0.932–1.329	0.614
CEA (ng/ml)	1.102	0.962–1.322	0.070
Differentiation	0.912	0.813–0.968	0.010*	0.858	0.771–0.972	0.025^*
Location	1.225	0.832–1.564	0.243
Ascending, transverse, and descending	1.000
Sigmoid	1.132	0.923–1.231	0.632
Rectum	1.342	0.831–1.532	0.452
Stage	1.332	1.024–2.012	0.002*	1.523	1.132–2.432	0.009*
I	1.000			1.000
II	1.028	0.821–1.223	0.298	1.131	0.882–1.251	0.328
III	2.852	1.852–3.832	0.001*	2.432	1.632–3.212	0.001*
MetS	1.621	1.221–2.133	0.007*	1.558	1.153–2.012	0.012*
NAFLD	1.544	1.031–1.893	0.010*	1.494	1.126–1.961	0.015*
Non	1.000			1.000
Mild	1.101	0.821–1.231	0.401	1.121	0.901–1.314	0.212
Moderate	1.452	1.113–2.371	0.001*	1.501	1.161–2.481	0.010*
Severe	1.612	1.224–2.471	0.010*	1.631	1.231–2.531	0.005*

NAFLD, non-alcoholic fatty livers disease, MetS metabolic syndrome, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein
^*represent the p value ≤ 0.05

ISSN: 1477-7819