Table 1 Patient characteristics of patients without and with adjuvant chemotherapy. In one patient, regression grade could not be determined
No adjuvant therapy (n = 50) | Adjuvant therapy (n = 54) | p value | |
|---|---|---|---|
Age | 62.9 ± 11.6 | 61.2 ± 9.8 | 0.414 |
Sex (female/male) | 36/14 | 40/14 | 0.829 |
Abdominoperineal resection | 10/50 | 11/54 | 1.0 |
Anastomotic leakage | 9/40 | 3/43 | 0.062 |
T stage | |||
ypT0 | 20 (40%) | 12 (22%) | 0.064 |
ypT1 | 6 (12%) | 8 (15%) | |
ypT2 | 24 (48%) | 34 (63%) | |
T stage | |||
ypT0–1 | 26 | 20 | 0.167 |
ypT2 | 24 | 34 | |
Lymph nodes retrieved | 13.1 ± 0.7 | 13.5 ± 0.7 | 0.687 |
Lymph nodes | |||
< 12 | 12 (24%) | 12 (22.2%) | 1.0 |
≥ 12 | 38 (76%) | 42(77.8%) | |
Regression grade (JSCCR) | |||
TRG 0 | 0 | 1 (2%) | 0.384 |
TRG 1 | 11 (22%) | 9 (17%) | |
TRG 2 | 20 (49%) | 32 (60%) | |
TRG 3 (pCR) | 18 (36%) | 12 (22%) | |