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Table 2 Treatment-related characteristics among age groups*

From: Do site and type of metastasis in breast cancer show a changing pattern with increased age? A cross comparison of clinicopathological characteristics between age groups

Variables

Group 1 (n = 564)†

Group 2 (n = 4519)

Group 3 (n = 670)

p value

Operation type

Mastectomy

219 (39)a

2235 (49.6)b

378 (57.3)c

< 0.001

Quadranectomy

342 (61)a

2270 (50.4)b

282(42.7)c

Type of recurrence

Local

6 (7.1)a

52 (7)a

9 (6.2)a

0.338

Regional

4 (4.7)a

11 (1.5)b

3 (2.1)b

Distant metastasis

75 (88.2)a

680 (91.5)a

133 (91.7)a

Site of metastasis

Liver

8 (13.3)a

69 (12.5)a

10 (11.4)a

< 0.001

Bone

21 (35)a

208 (37.5)a

28 (31.8)a

Lung

4 (6.7)a

70 (12.6)a

29 (33)b

Brain

8 (13.3)a

30 (5.4)b

1 (1.1)b

Others

8 (13.3)a

41 (7.4)a

11 (12.5)a

Mixed‡

11 (18.3)b

136 (24.5)b

9 (10.2)a

LN management

SLNB

130 (24.1)a

957 (22.3)a

104 (18.5)b

0.019

AND

343 (63.6)a

2885 (67.3)a

416 (73.9)b

Both

66 (12.2)a

443 (10.3)a

43 (7.6)b

No. of involved LN

 

3.93 ± 4.93a

3.17 ± 3.98a

2.21 ± 3.35a

0.10

Chemotherapy

Yes

494 (97.4)a

3640 (97)a

355 (76.7)b

< 0.001

No

13 (2.6)a

111 (3)a

108 (23.3)b

< 0.001

Radiotherapy

Yes

416 (89.7)a

2799 (81.6)b

247 (58.4)c

< 0.001

No

48 (10.3)a

630 (18.4)b

176 (41.6)c

Hormone therapy

Yes

327 (73.2)a

2746 (79)b

396 (86.1)c

< 0.001

No

120 (26.8)a

729 (21)b

64 (13.9)c

Type of hormone therapy

Tamoxifen

297 (91.7)a

1345 (49.5)b

29 (7.4)c

< 0.001

Latrazole

15 (4.6)a

1141 (42)b

341 (87)c

Both

11 (3.4)a

208 (7.7)b

14 (3.6)a

Other medications

1 (0.3)a

24 (0.9)a

8 (2)b

Recurrence

≤ 5 yr

42 (16.3)a

362 (11.7)b

46 (8.9)b

0.023

> 5 yr

4 (1.6)a

100 (3.2)a

19 (3.7)a

no

211 (82.1)a

2635 (85.1)b

452 (87.4)b

  1. SLNB sentinel lymph node biopsy, AND axillary node dissection, LN lymph node
  2. *Superscript alphabets represent the results of the post-hoc test, and accordingly, different alphabets show significant difference between groups. “a” is statistically different from “b” and “c”, “b” is statistically different from “a” and “c”, and “c” is statistically different from “a” and “b”
  3. †Age group 1 represent those younger than 30 years old, age group 2 represents those between 30 and 60 years old, and age group 3 represents those older than 60 years old
  4. ‡Mixed are those who had more than one site of metastasis