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Table 2 Treatment-related characteristics among age groups*

From: Do site and type of metastasis in breast cancer show a changing pattern with increased age? A cross comparison of clinicopathological characteristics between age groups

Variables Group 1 (n = 564)† Group 2 (n = 4519) Group 3 (n = 670) p value
Operation type Mastectomy 219 (39)a 2235 (49.6)b 378 (57.3)c < 0.001
Quadranectomy 342 (61)a 2270 (50.4)b 282(42.7)c
Type of recurrence Local 6 (7.1)a 52 (7)a 9 (6.2)a 0.338
Regional 4 (4.7)a 11 (1.5)b 3 (2.1)b
Distant metastasis 75 (88.2)a 680 (91.5)a 133 (91.7)a
Site of metastasis Liver 8 (13.3)a 69 (12.5)a 10 (11.4)a < 0.001
Bone 21 (35)a 208 (37.5)a 28 (31.8)a
Lung 4 (6.7)a 70 (12.6)a 29 (33)b
Brain 8 (13.3)a 30 (5.4)b 1 (1.1)b
Others 8 (13.3)a 41 (7.4)a 11 (12.5)a
Mixed‡ 11 (18.3)b 136 (24.5)b 9 (10.2)a
LN management SLNB 130 (24.1)a 957 (22.3)a 104 (18.5)b 0.019
AND 343 (63.6)a 2885 (67.3)a 416 (73.9)b
Both 66 (12.2)a 443 (10.3)a 43 (7.6)b
No. of involved LN   3.93 ± 4.93a 3.17 ± 3.98a 2.21 ± 3.35a 0.10
Chemotherapy Yes 494 (97.4)a 3640 (97)a 355 (76.7)b < 0.001
No 13 (2.6)a 111 (3)a 108 (23.3)b < 0.001
Radiotherapy Yes 416 (89.7)a 2799 (81.6)b 247 (58.4)c < 0.001
No 48 (10.3)a 630 (18.4)b 176 (41.6)c
Hormone therapy Yes 327 (73.2)a 2746 (79)b 396 (86.1)c < 0.001
No 120 (26.8)a 729 (21)b 64 (13.9)c
Type of hormone therapy Tamoxifen 297 (91.7)a 1345 (49.5)b 29 (7.4)c < 0.001
Latrazole 15 (4.6)a 1141 (42)b 341 (87)c
Both 11 (3.4)a 208 (7.7)b 14 (3.6)a
Other medications 1 (0.3)a 24 (0.9)a 8 (2)b
Recurrence ≤ 5 yr 42 (16.3)a 362 (11.7)b 46 (8.9)b 0.023
> 5 yr 4 (1.6)a 100 (3.2)a 19 (3.7)a
no 211 (82.1)a 2635 (85.1)b 452 (87.4)b
  1. SLNB sentinel lymph node biopsy, AND axillary node dissection, LN lymph node
  2. *Superscript alphabets represent the results of the post-hoc test, and accordingly, different alphabets show significant difference between groups. “a” is statistically different from “b” and “c”, “b” is statistically different from “a” and “c”, and “c” is statistically different from “a” and “b”
  3. †Age group 1 represent those younger than 30 years old, age group 2 represents those between 30 and 60 years old, and age group 3 represents those older than 60 years old
  4. ‡Mixed are those who had more than one site of metastasis