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Table 1 Risk and protective factors for CAC patients

From: Genomic characterization of colitis-associated colorectal cancer

Risk factors Protective factors
Young age onset Folic acid use
Family history of sporadic CRC UDCA use (in patients with PSC)
Long duration of IBD 5-ASA treatment
Increased extent of colitis Colectomy
PSC Compliance with CRC surveillance
Severity of colitis  
Dysplasia in UC  
  1. CAC colitis-associated cancer, CRC colorectal cancer, UDCA ursodeoxycholic acid, IBD inflammatory bowel disease, 5-ASA 5-aminosalicylic acid, PSC primary sclerosing cholangitis, UC ulcerative colitis