Fig. 2
From: Genomic characterization of colitis-associated colorectal cancer
Comparison of the frequency of genetic alterations in CAC and sporadic CRC. TP53 mutations are the most commonly occurring mutations in CAC. However, the mutations in APC are less frequent in CAC than in sporadic CRC. Genomic alteration patterns in Japanese and American patients are similar. CAC colitis-associated cancer, TCGA The Cancer Genome Atlas, FM Foundation Medicine, APC adenomatous polyposis coli, KRAS Kirsten rat sarcoma viral oncogene homolog, SMAD4 SMAD family member 4, IDH1 isocitrate dehydrogenase