|
Number of coursesa
|
2.3 ± 1.3
|
2.7 ± 1.2
|
0.303
|
|
Discontinuance of next course due to AE
|
6 (16.2)
|
2 (9.1)
|
0.440
|
|
Dose reduction
|
8 (21.6)
|
3 (13.6)
|
0.446
|
|
Hematologic toxicity (grades 3–4)
|
|
Neutropenia
|
30 (81.1)
|
9 (40.9)
|
0.002
|
|
Febrile neutropenia
|
5 (13.5)
|
2 (9.1)
|
0.612
|
|
Anemia
|
1 (2.7)
|
0
|
0.437
|
|
Thrombocytopenia
|
1 (2.7)
|
0
|
0.437
|
|
Non-hematologic toxicity (grades 3–4)
|
|
Nausea/vomiting
|
1 (2.7)
|
1 (4.5)
|
0.705
|
|
Diarrhea
|
10 (27)
|
5 (22.7)
|
0.714
|
|
Mucositis oral
|
6 (16.2)
|
1 (4.5)
|
0.180
|
|
Anorexia
|
7 (18.9)
|
0
|
0.030
|
|
Days to operationab (range)
|
52.3 ± 14.7 (30–86)
|
45.1 ± 13.5 (30–83)
|
0.067
|
|
Preoperative white blood cell count (/μL)a
|
5929.2 ± 2094
|
5017.3 ± 1777.7
|
0.091
|
|
Preoperative neutrophil count (/μL)a
|
3529.9 ± 1819.5
|
2950.2 ± 1313.1
|
0.199
|
