Fig. 3From: Therapeutic and prophylactic gastrectomy in a family with hereditary diffuse gastric cancer secondary to a CDH1 mutation: a case seriesPatient 2 gastric tissue biopsy. a High-power field of H&E staining of gastric mucosa with magnification on the right panel showing islet of signet ring cells (arrows) invading the lamina propria. b Immunohistochemistry (IHC) with cytokeratin 7 confirming tumor tissue infiltrating the lamina propriaBack to article page