Clinical value of miR-182-5p in lung squamous cell carcinoma: a study combining data from TCGA, GEO, and RT-qPCR validation

Table 3 Expression of miR-182-5p in the GEO microarrays

ID	Publication year	Tissue	n	Mean ± SD	t value	p value
GSE16025	2009	LUSC	60	6.718668 ± 0.7187121	11.157^a	< 0.001
GSE16025	2009	Non-cancerous	10	5.60987 ± 0.1125845	11.157^a	< 0.001
GSE25508	2011	LUSC	8	6.1557 ± 0.21346	1.060	0.307
GSE25508	2011	Non-cancerous	8	6.0497 ± 0.18564	1.060	0.307
GSE29248	2012	LUSC	3	8467.2363 ± 3393.2628	1.659	0.172
GSE29248	2012	Non-cancerous	3	5209.7237 ± 234.24406	1.659	0.172
GSE47525	2013	LUSC	5	2.1787 ± 0.34594	− 0.356	0.738
GSE47525	2013	Non-cancerous	14	2.2353 ± 0.13647	− 0.356	0.738
GSE19945	2013	LUSC	5	− 0.309311 ± 1.1072303	5.341	< 0.001
GSE19945	2013	Non-cancerous	8	− 2.79921 ± 0.5918523	5.341	< 0.001
GSE51853	2014	LUSC	29	1.048088 ± 0.8260201	6.576	< 0.001
GSE51853	2014	Non-cancerous	5	− 1.458859 ± 0.4262417	6.576	< 0.001
GSE74190	2015	LUSC	30	0.7706 ± 2.0075	7.417	< 0.001
GSE74190	2015	Non-cancerous	44	− 3.4043 ± 2.5973	7.417	< 0.001

Statistically significant results (p < 0.05) are indicated in bold
LUSC lung squamous cell carcinoma, SD standard deviation
^aStudent’s t test was used for comparison between the experimental and control groups

ISSN: 1477-7819