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Table 1 Demographic and disease profile

From: Evaluation of tumor M2-pyruvate kinase (Tumor M2-PK) as a biomarker for pancreatic cancer

Age (median––range)

66 (23–83)

Gender

Male 52 (71%)

Female 21 (29%)

Management

 Surgical treatment

65 (89%)

  Resection

55

   Pancreaticoduodenectomy

47

   Distal pancreatectomy + splenectomy

5

   Total pancreatectomy

2

   Central pancreatectomy

1

  No resection

10

   Palliative procedures

8

   Intraoperative biopsy only

2

 No surgical treatment

8 (11%)

Histology of resected specimen

 

 Malignant

46 (63%)

  Pancreatic ductal adenocarcinoma

18

  Ampullary adenocarcinoma

15

  Neuroendocrine tumor

6

  Distal bile duct cholangiocarcinoma

4

  Duodenal adenocarcinoma

2

  Pancreatic adenosquamous carcinoma

1

 Benign

9 (12%)

  Groove pancreatitis

2

  Chronic pancreatitis

2

  Ampullary tubulovillous adenoma

2

  Mucinous neoplasm

1

  Serous cystadenoma

1

  Solid pseudopapillary tumor

1

 Histology/cytology from biopsy

18 (25%)

  Pancreatic ductal/ampullary adenocarcinoma

8

  Neuroendocrine tumor

1

  Adenocarcinoma (frozen section)

5

  Histology not confirmed (clinical/radiological diagnosis)

4

Cancer differentiationa

  Well and moderately differentiated

34

  Poorly differentiated

16

Resection marginb

  R0

18

  R1

28

  1. R0 complete histological resection with at least 1-mm clear resection margin. R1 tumor reaches surgical resection margin
  2. aAvailable for 46 patients who underwent resection and a further 4 who underwent biopsy
  3. bApplies only to patients undergoing surgical resection for cancer
  4. The values in italics denote statistical significance