Table 2 Potential predictive factors and risk of SN metastases
Determinants | Category | SN negative | SN positive | OR 95% CI | OR 95% CIa |
|---|---|---|---|---|---|
Screening | No | 719 | 343 | 1.00 | 1.00 |
Yes | 1123 | 312 | 0.59(0.49–0.70) | 0.63(0.51–0.80) | |
Unknown | 39 | 16 | 0.86(0.48–1.57) | 0.88(0.46–1.66) | |
Age | ≤ 50 | 337 | 162 | 1.00 | 1.00 |
51–74 | 1290 | 412 | 0.67(0.53–0.82) | 0.92(0.63–1.37) | |
≥ 75 | 254 | 97 | 0.80(0.59–1.08) | 0.70(0.42–1.11) | |
Menopause Status | Pre | 348 | 164 | 1.00 | 1.00 |
Post < 5 years | 168 | 60 | 0.76(0.53–1.08) | 0.98(0.62–1.53) | |
Post ≥ 5years | 1299 | 422 | 0.69(0.56–0.86) | 0.82(0.56–1.22) | |
Unknown | 66 | 25 | 0.80(0.49–1.32) | 0.89(0.50–1.53) | |
Tumor size | T1 | 1138 | 367 | 1.00 | 1.00 |
T2 | 346 | 213 | 1.91(1.56–2.34) | 1.84(1.47–2.33) | |
T3 and T4 | 13 | 12 | 2.87(1.30–6.32) | 2.56(1.07–6.09) | |
Unknown | 384 | 79 | 0.63(0.49–0.83) | 0.67(0.50–0.93) | |
Tumor type | Ductal | 1325 | 542 | 1.00 | 1.00 |
D and L | 35 | 17 | 1.19(0.66–2.13) | 1.01 (0.54–1.90) | |
Lobular | 217 | 88 | 1.00(0.77–1.30) | 0.87(0.64–1.20) | |
Others | 306 | 24 | 0.20(0.12–0.30) | 0.29(0.18–0.46) | |
Histological grade | I | 488 | 134 | 1.00 | 1.00 |
II | 807 | 305 | 1.37(1.09–1.73) | 1.02(0.80–1.31) | |
III | 563 | 227 | 1.46(1.14–1.87) | 1.10(0.82–1.50) | |
Unknown | 23 | 5 | 0.79(0.29–2.12) | 1.40(0.46–4.31) | |
Estrogen receptor | Positive | 1538 | 606 | 1.00 | 1.00 |
Negative | 218 | 61 | 0.71(0.52–0.96) | 0.64(0.42–0.99) | |
Unknown | 125 | 4 | 0.09(0.03–0.22) | 0.06(0.00–0.82) | |
Progesterone receptor | Positive | 1320 | 531 | 1.00 | 1.00 |
Negative | 436 | 135 | 0.77(0.61–0.96) | 0.78(0.56–1.07) | |
Unknown | 125 | 5 | 0.10(0.04–0.24) | 3.80(0.30–47.42) | |
Her-2 status | Negative | 1041 | 423 | 1.00 | 1.00 |
Positive | 174 | 66 | 0.93(0.69–1.27) | 0.84(0.60–1.20) | |
Unknown | 666 | 182 | 0.68(0.56–0.82) | 0.98(0.78–1.24) | |
Multifocality | No | 1184 | 386 | 1.00 | 1.00 |
Yes | 208 | 144 | 2.12(1.67–2.70) | 1.90(1.45–2.47) | |
Unknown | 489 | 141 | 0.89(0.71–1.10) | 0.86(0.67–1.09) | |
Vascular invasion | No | 1056 | 268 | 1.00 | 1.00 |
Yes | 87 | 97 | 4.40(3.20–6.04) | 3.74(2.66–5.27) | |
Unknown | 738 | 306 | 1.63(1.36–1.98) | 2.10(1.68–2.62) |