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Table 1 Clinical and pathological characteristics of the included studies

From: Associating liver partition and portal vein ligation for staged hepatectomy versus conventional two-stage hepatectomy: a systematic review and meta-analysis

Author Year No. of patients Preoperative chemotherapy Tumor size (mm) TNM stage Comparable variables Level Study design Quality score
Knoefel et al. [14] 2012 ALPPS(7) PVE(15) 5 NI NI NI 1, 3, 7 4 RCS 6
Shindoh et al. [19] 2013 ALPPS(25) PVE(144) 12 94 NI NI 1, 2, 5, 7 3 RCS 7
Croome et al. [13] 2014 ALPPS(15) PVE(53) 14 40 NI NI 1, 2, 5, 7, 9 3 RCS 8
Schadde et al. [18] 2014 ALPPS(48) PVE/PVL(83) 28 44 NI NI 1, 2, 4, 5, 7, 8, 9 3 RCS 9
Ratti et al. [16] 2015 ALPPS(12) PVE/PVL(36) 9 30 NI NI 1, 2, 5, 6, 7, 8, 9 3 RCS 9
Matsuo et al. [15] 2015 ALPPS(8) PVE(14) 8 12 21 35.5 NI 1, 2, 3, 5, 7 4 RCS 6
Tanaka et al. [20] 2015 ALPPS(11) PVE/PVL(54) 11 47 22 40.5 NI 1, 2, 7 4 RCS 7
Adam et al. [11] 2016 ALPPS(17) PVE/PVL(41) 17 41 40 50 NI 1, 2, 5, 6, 7, 8 4 RCS 7
Chia et al. [12] 2017 ALPPS(10) PVE/PVL(29) 3 16 81 66 NI 1, 2, 4, 5, 7 4 RCS 7
Sandström et al. [17] 2017 ALPPS(48) PVE/PVL(49) NI NI 54 49 NI 1, 2, 3, 5, 7, 8, 9 1 RCT 8
  1. 1: age; 2: preoperative chemotherapy; 3: preoperative liver function; 4: pathology state before operation; 5: pathology type of tumor; 6: pathology stage; 7: sex; 8: ASA score; 9: BMI
  2. NI no information, RCS retrospective cohort study, RCT randomized controlled trial