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Table 1 Correlation of clinicopathological parameters with Foxp3 and VEGF-C in cervical cancer patients

From: Foxp3 is correlated with VEGF-C expression and lymphangiogenesis in cervical cancer

Clinical parameter Foxp3 expression P value VEGF-C expression P value
Positive (%) Negative (%) Positive (%) Negative(%)  
Age (year)
 < 50 14 (28) 10 (20)   20 (40) 4 (8)  
 ≥ 50 19 (38) 7 (14) 0.373 18 (36) 8(16) 0.327
Differentiation
 High + moderate 17(34) 8 (16)   23 (46) 4 (8)  
 Low 16(32) 9 (18) 1.000 15 (30) 8(16) 0.183
Tumor size
 < 4 cm 12 (24) 9 (18)   16 (32) 5 (10)  
 ≥ 4 cm 21 (42) 8 (16) 0.366 22 (44) 7 (14) 0.624
Histological type
 Squamous carcinoma 30 (60) 12 (24)   34 (68) 8(16)  
 Adenocarcinoma 3 (6) 5 (10) 0.102 4 (8) 4 (8) 0.082
Clinical stage
 I + II 19(38) 16 (32)   30(60) 5(10)  
 III + IV 14(28) 1(2) 0.009 8 (16) 7 (14) 0.027
Lymph node metastasis
 Absent 19(38) 15(30)   23 (46) 11(22)  
 Present 14(28) 2(4) 0.026 15 (30) 1 (2) 0.042