Table 2 Characteristics of the study subjects
Variable | Discovery set | Validation set | ||||
|---|---|---|---|---|---|---|
patients | Controls | P | Patients | Controls | P | |
(N = 416) | (N = 416) | (N = 505) | (N = 505) | |||
Age | 0.532 | 0.184 | ||||
< 60 | 191 (45.9) | 200 (48.1) | 217 (43.0) | 238 (47.1) | ||
≥ 60 | 225 (54.1) | 216 (51.9) | 288 (57.0) | 267 (52.9) | ||
Gender | 0.357 | 0.477 | ||||
Male | 245 (58.9) | 258 (62.0) | 316 (62.6) | 305 (60.4) | ||
Female | 171 (41.1) | 158 (38.0) | 189 (37.4) | 200 (39.6) | ||
Body mass index | 0.329 | 0.613 | ||||
< 23 | 178 (42.8) | 192 (46.2) | 227 (45.0) | 235 (46.5) | ||
≥ 23 | 238 (57.2) | 224 (53.8) | 278 (55.0) | 270 (53.5) | ||
Smoking status | 0.363 | 0.334 | ||||
No | 229 (55.0) | 242 (58.2) | 298 (59.0) | 313 (62.0) | ||
Yes | 187 (45.0) | 174 (41.8) | 207 (41.0) | 192 (38.0) | ||
Alcohol consumer | 0.360 | 0.339 | ||||
No | 237 (57.0) | 250 (60.1) | 300 (59.4) | 285 (56.4) | ||
Yes | 179 (43.0) | 166 (39.9) | 205 (40.6) | 220 (43.6) | ||
Hypertension | 0.082 | 0.067 | ||||
No | 297 (71.4) | 319 (76.7) | 353 (69.9) | 379 (75.0) | ||
Yes | 119 (28.6) | 97 (23.3) | 152 (30.1) | 126 (25.0) | ||
History of pancreatitis | 0.003 | 0.001 | ||||
No | 400 (96.2) | 413 (99.3) | 481 (95.2) | 499 (98.8) | ||
Yes | 16 (3.8) | 3 (0.7) | 24 (4.8) | 6 (1.2) | ||
History of diabetes mellitus | < 0.001 | <0.001 | ||||
No | 332 (79.8) | 383 (92.1) | 409 (81.0) | 460 (91.1) | ||
Yes | 84 (20.2) | 33 (7.9) | 96 (19.0) | 45 (8.9) | ||
Family history of cancer | 0.002 | 0.003 | ||||
No | 394 (94.7) | 410 (98.6) | 480 (95.0) | 497 (98.4) | ||
Yes | 22 (5.3) | 6 (1.4) | 25 (5.0) | 8 (1.6) | ||