Skip to main content

Table 2 Characteristics of the study subjects

From: rs1859168 A > C polymorphism regulates HOTTIP expression and reduces risk of pancreatic cancer in a Chinese population

Variable Discovery set Validation set
patients Controls P Patients Controls P
(N = 416) (N = 416) (N = 505) (N = 505)
Age    0.532    0.184
  < 60 191 (45.9) 200 (48.1)   217 (43.0) 238 (47.1)  
  ≥ 60 225 (54.1) 216 (51.9)   288 (57.0) 267 (52.9)  
Gender    0.357    0.477
 Male 245 (58.9) 258 (62.0)   316 (62.6) 305 (60.4)  
 Female 171 (41.1) 158 (38.0)   189 (37.4) 200 (39.6)  
Body mass index    0.329    0.613
  < 23 178 (42.8) 192 (46.2)   227 (45.0) 235 (46.5)  
  ≥ 23 238 (57.2) 224 (53.8)   278 (55.0) 270 (53.5)  
Smoking status    0.363    0.334
 No 229 (55.0) 242 (58.2)   298 (59.0) 313 (62.0)  
 Yes 187 (45.0) 174 (41.8)   207 (41.0) 192 (38.0)  
Alcohol consumer    0.360    0.339
 No 237 (57.0) 250 (60.1)   300 (59.4) 285 (56.4)  
 Yes 179 (43.0) 166 (39.9)   205 (40.6) 220 (43.6)  
Hypertension    0.082    0.067
 No 297 (71.4) 319 (76.7)   353 (69.9) 379 (75.0)  
 Yes 119 (28.6) 97 (23.3)   152 (30.1) 126 (25.0)  
History of pancreatitis    0.003    0.001
 No 400 (96.2) 413 (99.3)   481 (95.2) 499 (98.8)  
 Yes 16 (3.8) 3 (0.7)   24 (4.8) 6 (1.2)  
History of diabetes mellitus    < 0.001    <0.001
 No 332 (79.8) 383 (92.1)   409 (81.0) 460 (91.1)  
 Yes 84 (20.2) 33 (7.9)   96 (19.0) 45 (8.9)  
Family history of cancer    0.002    0.003
 No 394 (94.7) 410 (98.6)   480 (95.0) 497 (98.4)  
 Yes 22 (5.3) 6 (1.4)   25 (5.0) 8 (1.6)