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Table 2 Antibodies used in this study

From: Two different protein expression profiles of oral squamous cell carcinoma analyzed by immunoprecipitation high-performance liquid chromatography

Signaling proteins Number Antibodies
Cytoskeletal proteins 1 α-Tubulina
Growth factor-related proteins 5 EGFRb, c-erbB2b, TGF-β1d, bFGFa, HGFb
Proliferation-related proteins 9 eIF5Ac, DHSc, DOHHc, PCNAc, MPM-2b, CDK4a, cMyca, MAXa, hTERTa
Transcription signaling proteins 3 NFkBb, p38a, E2F-1a
Apoptosis-related proteins 14 FASa, FASLa, PARPa, BAXa, NOXAa, PUMAa, BADa, BAKa, BIDa, caspase 3a, caspase 8a, caspase 9a, FADDa, FLIPa,
Cell survival-related proteins 3 pAKTc, MDM2a, BCL2a
Tumor suppressor proteins 8 p16a, p21a, p53a, p63a, RB1a, PTENa, PTCHa, NF-1b
Oncoproteins 9 14-3-3a, CEAc, STAT3a, survivind, DMBT1a, maspina, snaila, KRASc, PIM1a
Protection proteins 5 HO-1a, caveolina, HSP-70a, FAKa, TGase-1b
Proinflammation proteins 2 TNFα, SHP-1
WNT/β-catenin pathway proteins 4 SHHa, β-cateninb, WNT1a, APCa
Matrix proteolysis proteins 4 MMP-1c, MMP-2c, MMP-9a, elaffina
Angiogenesis-related proteins 5 HIFd, VEGFd, vWFc, angiogenina , CMG2b
Total 72  
  1. Abbreviation: pAKT v-akt murine thymoma viral oncogene homolog (phosphorylated at Thr 308), APC adenomatous polyposis coli, BAD BCL2 associated death promoter, BAK BCL2 antagonist/killer, BAX BCL2 associated X, BCL-2 B-cell leukemia/lymphoma-2, BID BH3 interacting-domain death agonist, CDK4 cyclin dependent kinase 4, CEA carcinoembryonic antigen, CMG2 capillary morphogenesis protein 2, DHS deoxyhypusine synthase, DOHH deoxyhypusine hydroxylase, DMBT1 deleted in malignant brain tumors 1, E2F-1 transcription factor, EGFR epithelial growth factor receptor, eIF5A eukaryotic translation initiation factor 5A, FADD FAS associated via death domain, FAK focal adhesion kinase, FAS CD95/Apo1, FASL FAS ligand, bFGF basic fibroblast growth factor, FLIP FLICE-like inhibitory protein, HGF hepatocyte growth factor, HIF hypoxia inducible factor, HO-1 hemoxygenase 1, HSP-70 heat shock protein-70, KRAS V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, MAX myc-associated factor X, MDM2 mouse double minute 2 homolog, MMP-1 matrix metalloprotease-1, MPM-2 mitotic protein monoclonal 2, cMyc V-myc myelocytomatosis viral oncogene homolog (avian), NF-1 neurofibromin-1, NFkB nuclear factor kappa-light-chain-enhancer of activated B cells; NOXA phorbol-12-myristate-13-acetate-induced protein 1; PARP poly-ADP ribose polymerase, PCNA proliferating cell nuclear antigen, PIM1 pivotal integration site 1, PTCH patched homolog, PTEN phosphatase and tensin homolog, PUMA p53 up-regulated modulator of apoptosis, RB1 retinoblastoma 1, SHH sonic hedgehog, SHP-1 short helical protein-1, SOS-1 Son of sevenless-1, STAT3 signal transducer and activator of transcription-3, hTERT human telomerase reverse transcriptase, TGase-1 transglutaminase-1, TGF-β1 transforming growth factor-β1, TNFα tumor necrosis factor-α, VEGF vascular endothelial growth factor, vWF von Willebrand factor
  2. aSanta Cruz Biotechnology, USA
  3. bDAKO, Denmark
  4. cNeomarkers, CA, USA
  5. dZYMED, CA, USA