Fig. 3From: Metachronous colorectal carcinoma with massive submucosal invasion detected by annual surveillance in a Lynch syndrome patient: a case reportImmunohistochemical staining of the colon cancer. The colon cancer stained negative for MLH1 and PMS2 and positive for MSH6 and MSH2 (×400), which was in agreement with the germline mutation in MLH1 Back to article page