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Table 4 Univariate and multivariate analyses for RSCCs and LSCRs

From: Primary tumor location as a predictor of the benefit of palliative resection for colorectal cancer with unresectable metastasis

 

Overall survival

RSCCs

LSCRs

Univariate

Multivariate

Univariate

Multivariate

Variable

RR (95% CI)

P

RR (95% CI)

P

RR (95% CI)

P

RR (95% CI)

P

T stage

2.284 (0.205–25.41)

0.502

  

0.271 (0.064–1.141)

0.075

  

LVI

1.219 (0.449–3.306)

0.697

  

1.198 (0.794–1.807)

0.389

  

PNI

0.595 (0.211–2.441)

0.717

  

1.913 (0.806–.542)

0.142

  

N stage

0.911 (0.267–4.717)

0.847

  

0.566 (0.131–2.445)

0.446

  

Regional LNs

0.973 (0.913–1.036)

0.388

  

0.90 (.929–.013)

0.170

  

Metastasis LNs

1.040 (0.960–1.126)

0.336

  

1.04 (0.987–1.112)

0.123

  

Sex

1.363 (0.693–2.681)

0.369

  

1.143 (0.735–1.778)

0.553

  

Diameter of LM

1.705 (0.833–3.491)

0.144

  

1.75 (.153–2.656)

0.009

  

Neo-chemo

2.263 (0.931–5.504)

0.072

  

0.846 (0.424–1.686)

0.635

  

Histological type

2.696 (1.327–5.476)

0.006

0.313 (0.134–0.729)

0.02

0.519 (0.203–0.923)

0.001

0.346 (0.131–0.913)

0.032

CA199

0.826 (0.426–1.621)

0.578

  

2.087 (1.371–3.177)

0.001

  

Number of LM

1.864 (0.886–3.923)

0.101

  

2.022 (1.274–3.211)

0.003

2.183 (1.243–3.833)

0.007

CEA

1.075 (0.503–2.300)

0.852

  

2.310 (1.42–624)

0.001

  

Systemic chemo

0.620 (0.267–1.442)

0.267

  

0.830 (0.462–1.492)

0.533

  

Palliative resection

1.041 (0.500–2.179)

0.910

  

1.767 (11.15–2.716)

0.009

1.767 (1.150–2.716)

0.011

  1. RSCC right-side colon cancer, LSCRC left-side colorectal cancer, RR risk ratio, CI confidence interval, LVI lymphovascular invasion, PNI perineural invasion, LNs lymph nodes, LM liver metastasis, Neo-chemo neoadjuvant chemotherapy, CEA carcinoembryonic antigen, CA cancer antigen