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Table 3 Overall deaths/breast cancer deaths, crude and adjusted comparing BCT to MTX

From: Better survival after breast-conserving therapy compared to mastectomy when axillary node status is positive in early-stage breast cancer: a registry-based follow-up study of 6387 Norwegian women participating in screening, primarily operated between 1998 and 2009

  Crude Adjusted
Overall death
(95% CI)
Breast cancer death
(95% CI)
Overall death
(95% CI)
Breast cancer death
(95% CI)
Surgery (adjusted stage)
 BCT 1 1 1 1
 MTX 1.91 (1.56–2.33) 2.33 (1.75–3.10) 1.43 (1.16–1.77) 1.39 (1.02–1.89)
Screening
 First screening 1 1 1 1
 Second or later 0.96 (0.74–1.24) 0.88 (0.60–1.30) 0.91 (0.69–1.18) 0.90 (0.61–1.36)
 Interval cancer 1.65 (1.25–2.18) 2.39 (1.62–3.52) 1.12 (0.83–1.50) 1.32 (0.87–2.00)
Year of diagnosis
 1998–2004 1 1 1 1
 2005–2009 0.58 (0.45–0.75) 0.49 (0.34–0.71) 0.59 (0.45–0.76) 0.48 (0.33–0.70)
Screening age
 50–53 1 1 1 1
 54–57 1.65 (1.13–2.41) 1.60 (1.00–2.59) 1.69 (1.15–2.49) 1.62 (0.99–2.64)
 58–61 1.80 (1.24–2.59) 1.45 (0.90–2.34) 1.95 (1.34–2.84) 1.65 (1.01–2.69)
 62–65 1.94 (1.34–2.88) 1.26 (0.77–2.09) 2.18 (1.49–3.18) 1.47 (0.88–2.46)
 66–69 2.29 (1.58–3.32) 1.26 (0.74–2.13) 2.61 (1.78–3.82) 1.59 (0.93–2.72)
Tumor size
 T1 ≤ 2 cm 1 1 1 1
 T2 > 2–5 ≤ cm 2.27 (1.83–2.81) 3.86 (2.90–5.15) 1.52 (1.22–1.97) 2.08 (1.51–2.86)
Nodal status
 Negative node 1 1 1 1
 1 positive node 1.45 (1.10–1.90) 2.09 (1.46–2.99) 1.32 (1.00–1.74) 1.65 (1.15–2.38)
 2 positive nodes 1.70 (1.14–2.52) 2.48 (1.49–4.12) 1.33 (0.89–1.99) 1.55 (0.92–2.62)
 3 positive nodes 2.39 (1.49–3.85) 3.68 (2.03–6.66) 1.67 (1.02–2.72) 1.96 (1.06–3.63)
Histology
 Ductal carcinoma 1 1 1 1
 Lobular carcinoma 0.77 (0.53–1.13) 0.73 (0.42–1.26) 0.77 (0.52–1.14) 0.85 (0.48–1.49)
 Other carcinoma 0.96 (0.68–1.36) 0.89 (0.53–1.49) 0.96 (0.67–1.36) 0.83 (0.49–1.40)
Grade
 Grade1 1 1 1 1
 Grade2 1.57 (1.21–2.03) 2.48 (1.57–3.91) 1.34 (1.02–1.76) 1.83 (1.15–2.92)
 Grade3 3.05 (2.31–4.04) 7.58 (4.81–11.93) 1.66 (1.19–2.31) 2.91 (1.73–4.88)
 Unknown grade 1.17 (0.51–2.69) 4.64 (no value) 0.84 (0.36–1.96) Missing
Hormone status
 Positive 1 1 1 1
 Intermediate 1.66 (1.05–2.61) 3.61 (2.17–6.03) 1.41 (0.89–2.24) 2.48 (1.47–4.20)
 Negative 2.83 (2.24–3.58) 5.01 (3.68–6.82) 1.98 (1.50–2.62) 2.61 (1.80–3.79)