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Table 3 Overall deaths/breast cancer deaths, crude and adjusted comparing BCT to MTX

From: Better survival after breast-conserving therapy compared to mastectomy when axillary node status is positive in early-stage breast cancer: a registry-based follow-up study of 6387 Norwegian women participating in screening, primarily operated between 1998 and 2009

 

Crude

Adjusted

Overall death

(95% CI)

Breast cancer death

(95% CI)

Overall death

(95% CI)

Breast cancer death

(95% CI)

Surgery (adjusted stage)

 BCT

1

1

1

1

 MTX

1.91 (1.56–2.33)

2.33 (1.75–3.10)

1.43 (1.16–1.77)

1.39 (1.02–1.89)

Screening

 First screening

1

1

1

1

 Second or later

0.96 (0.74–1.24)

0.88 (0.60–1.30)

0.91 (0.69–1.18)

0.90 (0.61–1.36)

 Interval cancer

1.65 (1.25–2.18)

2.39 (1.62–3.52)

1.12 (0.83–1.50)

1.32 (0.87–2.00)

Year of diagnosis

 1998–2004

1

1

1

1

 2005–2009

0.58 (0.45–0.75)

0.49 (0.34–0.71)

0.59 (0.45–0.76)

0.48 (0.33–0.70)

Screening age

 50–53

1

1

1

1

 54–57

1.65 (1.13–2.41)

1.60 (1.00–2.59)

1.69 (1.15–2.49)

1.62 (0.99–2.64)

 58–61

1.80 (1.24–2.59)

1.45 (0.90–2.34)

1.95 (1.34–2.84)

1.65 (1.01–2.69)

 62–65

1.94 (1.34–2.88)

1.26 (0.77–2.09)

2.18 (1.49–3.18)

1.47 (0.88–2.46)

 66–69

2.29 (1.58–3.32)

1.26 (0.74–2.13)

2.61 (1.78–3.82)

1.59 (0.93–2.72)

Tumor size

 T1 ≤ 2 cm

1

1

1

1

 T2 > 2–5 ≤ cm

2.27 (1.83–2.81)

3.86 (2.90–5.15)

1.52 (1.22–1.97)

2.08 (1.51–2.86)

Nodal status

 Negative node

1

1

1

1

 1 positive node

1.45 (1.10–1.90)

2.09 (1.46–2.99)

1.32 (1.00–1.74)

1.65 (1.15–2.38)

 2 positive nodes

1.70 (1.14–2.52)

2.48 (1.49–4.12)

1.33 (0.89–1.99)

1.55 (0.92–2.62)

 3 positive nodes

2.39 (1.49–3.85)

3.68 (2.03–6.66)

1.67 (1.02–2.72)

1.96 (1.06–3.63)

Histology

 Ductal carcinoma

1

1

1

1

 Lobular carcinoma

0.77 (0.53–1.13)

0.73 (0.42–1.26)

0.77 (0.52–1.14)

0.85 (0.48–1.49)

 Other carcinoma

0.96 (0.68–1.36)

0.89 (0.53–1.49)

0.96 (0.67–1.36)

0.83 (0.49–1.40)

Grade

 Grade1

1

1

1

1

 Grade2

1.57 (1.21–2.03)

2.48 (1.57–3.91)

1.34 (1.02–1.76)

1.83 (1.15–2.92)

 Grade3

3.05 (2.31–4.04)

7.58 (4.81–11.93)

1.66 (1.19–2.31)

2.91 (1.73–4.88)

 Unknown grade

1.17 (0.51–2.69)

4.64 (no value)

0.84 (0.36–1.96)

Missing

Hormone status

 Positive

1

1

1

1

 Intermediate

1.66 (1.05–2.61)

3.61 (2.17–6.03)

1.41 (0.89–2.24)

2.48 (1.47–4.20)

 Negative

2.83 (2.24–3.58)

5.01 (3.68–6.82)

1.98 (1.50–2.62)

2.61 (1.80–3.79)