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Table 4 Allele frequency and genotype distribution of hTERT rs2736100 and rs2736098 polymorphisms between the recurrence and non-recurrence groups

From: The correlations between DNA methylation and polymorphisms in the promoter region of the human telomerase reverse transcriptase (hTERT) gene with postoperative recurrence in patients with thyroid carcinoma (TC)

  Non-recurrence group Recurrence group P OR (95%CI)
  (n = 237) (n = 75)   
rs2736100
 TT genotype 54 (22.8) 7 (9.3) Ref  
 TG genotype 133 (56.1) 39 (52.0) 0.059 0.44 (0.19–1.05)
 GG genotype 50 (21.1) 29 (38.7) 0.001 4.47 (1.80–11.12)
 T allele 241 (50.8) 53 (35.3) Ref  
 G allele 233 (49.2) 97 (64.7) 0.001 1.89 (1.29–2.77)
rs2736098     
 GG genotype 135 (57.0) 46 (61.3) Ref  
 GA genotype 86 (36.3) 26 (34.7) 0.671 0.89 (0.51–1.54)
 AA genotype 16 (6.8) 3 (4.0) 0.353 0.55 (0.15–1.98)
 G allele 356 (75.1) 118 (78.7) Ref  
 A allele 118 (24.9) 32 (21.3) 0.373 0.82 (0.53–1.27)
  1. hTERT human telomerase reverse transcriptase, Ref reference, OR odds ratio, CI confidence interval