Table 2 Comparison of the QLQ-c30 overall QoL/general health scale scores of TM-ILP patients and three reference cohorts
From: Lower limb function and quality of life after ILP for soft-tissue sarcoma
TM-ILP patients | Amputation [23] | General population [31] | All cancer patients [31] | |
|---|---|---|---|---|
Mean | 76.6 | 69 | 71.2 | 61.3* |
SD | 18.7 | 11 | 22.4 | 24.2 |
N | 26 | 22 | 7802 | 23,553 |
Margin of error (5%) | 7.6 | 4.9 | 0.5 | 0.3 |
95% CI (lower) | 84.2 | 73.9 | 71.7 | 61.6 |
95% CI (upper) | 69.0 | 64.1 | 70.7 | 61.0 |
p (2-sample t test vs. TM-ILP patients) | 0.1007 | 0.2196 | 0.0013 | |
Order of p low to high (Bonferroni-Holm) | 2 | 3 | 1 | |
Comparison to Bonferroni-Holm-corrected alpha-level | 0.025 | 0.05 | 0.0167 | |
Result of significance testing according to Bonferroni-Holm | n.s. | n.s. | Significant | |
Effect size (Cohen’s d) | 0.49 | 0.24 | 0.63 |