Fig. 3
From: Orchitis reveals an extragonadal primary mediastinal thymic seminoma: a coincidence or not?
a Seminoma, note admixed lymphocytes (H-Ex10). b Seminoma showing clear cytoplasm with distinct membranes and round to polygonal nuclei with large nucleoli (H-Ex20). c Seminoma showing a characteristic diffuse pattern interrupted by fibrous septa with a lymphocytic infiltrate and with prominent granulomatous inflammation (H-E x5). d Negative stain for Pan-CK (×20). e Cytoplasmic membrane negative stain for SOX2 (×20). f Cytoplasmic membrane negative stain for CD30 (×20). g Cytoplasmic membrane positive stain for D2-40 (×40). h Cytoplasmic membrane positive stain for PLAP (×40). i Cytoplasmic membrane positive stain for c-kit (×40)