Table 4 Association between CRP and clinicopathologic parameters in tongue cancer (n = 132)
From: Roles of preoperative C-reactive protein are more relevant in buccal cancer than other subsites
Characteristic | CRP | p value | |||
|---|---|---|---|---|---|
Negative | Positive | ||||
Pathologic tumor status | |||||
 Early (T1–T2) (n = 96) | 83 | (86.5%) | 13 | (13.5%) | <0.001 |
 Advanced (T3–T4) (n = 36) | 19 | (52.8%) | 17 | (47.2%) |  |
Pathologic N stage | |||||
 N0 (n = 77) | 64 | (83.1%) | 13 | (16.9%) | 0.027 |
 N1 (n = 15) | 13 | (86.7%) | 2 | (13.3%) | 0.017 a |
 N2 (n = 40) | 25 | (62.5%) | 15 | (37.5%) |  |
Nodal status | |||||
 (−) metastasis, (−) ECS (n = 77) | 64 | (83.1%) | 13 | (16.9%) | 0.163 |
 (+) metastasis, (−) ECS (n = 17) | 12 | (70.6%) | 5 | (29.4%) | 0.066a |
 (+) metastasis, (+) ECS (n = 38) | 26 | (68.4%) | 12 | (31.6%) |  |
Differentiation | |||||
 Well (n = 33) | 28 | (84.8%) | 5 | (15.2%) | 0.152 |
 Moderate (n = 81) | 63 | (77.8%) | 18 | (22.2%) |  |
 Poor (n = 18) | 11 | (61.1%) | 7 | (38.9%) |  |
Tumor stage | |||||
 Early (I–II) (n = 64) | 55 | (85.9%) | 9 | (14.1%) | 0.021 |
 Advanced (III–IV) (n = 68) | 47 | (69.1%) | 21 | (30.9%) |  |
Skin invasion | |||||
 No (n = 131) | 101 | (77.1%) | 30 | (22.9%) | 1.000 |
 Yes (n = 1) | 1 | (100.0%) | 0 | (0.0%) |  |
Nerve invasion | |||||
 No (n = 77) | 60 | (77.9%) | 17 | (22.1%) | 0.833 |
 Yes (n = 55) | 42 | (76.4%) | 13 | (23.6%) |  |
Blood vessel invasion | |||||
 No (n = 130) | 100 | (76.9%) | 30 | (23.1%) | 1.000b |
 Yes (n = 2) | 2 | (100.0%) | 0 | (0.0%) |  |
Lymphatic invasion | |||||
 No (n = 129) | 101 | (78.3%) | 28 | (21.7%) | 0.129b |
 Yes (n = 3) | 1 | (33.3%) | 2 | (66.7%) |  |
Tumor depth (≥10 mm) | |||||
 No (n = 58) | 49 | (84.5%) | 9 | (15.5%) | 0.080 |
 Yes (n = 74) | 53 | (71.6%) | 21 | (28.4%) |  |
Bone invasion | |||||
 No (n = 129) | 100 | (77.5%) | 29 | (22.5%) | 0.542b |
 Yes (n = 3) | 2 | (66.7%) | 1 | (33.3%) |  |