Table 3 Association between CRP and clinicopathologic parameters in buccal cancer (n = 126)
From: Roles of preoperative C-reactive protein are more relevant in buccal cancer than other subsites
Characteristic | CRP | p value | |||
|---|---|---|---|---|---|
Negative | Positive | ||||
Pathologic tumor status | |||||
 Early (T1–T2) (n = 71) | 60 | (84.5%) | 11 | (15.5%) | <0.001 |
 Advanced (T3–T4) (n = 55) | 25 | (45.5%) | 30 | (54.5%) |  |
Pathologic N stage | |||||
 N0 (n = 70) | 52 | (74.3%) | 18 | (25.7%) | 0.009 |
 N1 (n = 18) | 15 | (83.3%) | 3 | (16.7%) | 0.006 a |
 N2 (n = 37) | 18 | (48.6%) | 19 | (51.4%) |  |
 N3 (n = 1) | 0 | (0.0%) | 1 | (100.0%) |  |
Nodal status | |||||
 (−) metastasis, (−) ECS (n = 70) | 52 | (74.3%) | 18 | (25.7%) | 0.003 |
 (+) metastasis, (−) ECS (n = 27) | 21 | (77.8%) | 6 | (22.2%) | 0.005 a |
 (+) metastasis, (+) ECS (n = 29) | 12 | (41.4%) | 17 | (58.6%) |  |
Differentiation | |||||
 Well (n = 48) | 28 | (58.3%) | 20 | (41.7%) | 0.211 |
 Moderate (n = 62) | 46 | (74.2%) | 16 | (25.8%) | 0.192a |
 Poor (n = 16) | 11 | (68.8%) | 5 | (31.2%) |  |
Tumor stage | |||||
 Early (I–II) (n = 48) | 41 | (85.4%) | 7 | (14.6%) | 0.001 |
 Advanced (III–IV) (n = 78) | 44 | (56.4%) | 34 | (43.6%) |  |
Skin invasion | |||||
 No (n = 96) | 73 | (76.0%) | 23 | (24.0%) | <0.001 |
 Yes (n = 30) | 12 | (40.0%) | 18 | (60.0%) |  |
Nerve invasion | |||||
 No (n = 86) | 63 | (73.3%) | 23 | (26.7%) | 0.042 |
 Yes (n = 40) | 22 | (55.0%) | 18 | (45.0%) |  |
Blood vessel invasion | |||||
 No (n = 122) | 83 | (68.0%) | 39 | (32.0%) | 0.595b |
 Yes (n = 4) | 2 | (50.0%) | 2 | (50.0%) |  |
Lymphatic invasion | |||||
 No (n = 122) | 84 | (68.9%) | 38 | (31.1%) | 0.101b |
 Yes (n = 4) | 1 | (25.0%) | 3 | (75.0%) |  |
Tumor depth ≥10 mm | |||||
 No (n = 60) | 52 | (86.7%) | 8 | (13.3%) | <0.001 |
 Yes (n = 66) | 33 | (50.0%) | 33 | (50.0%) |  |
Bone invasion | |||||
 No (n = 92) | 68 | (73.9%) | 24 | (26.1%) | 0.011 |
 Yes (n = 34) | 17 | (50.0%) | 17 | (50.0%) |  |