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Table 1 Clinical features of 57 patients with KTs of colorectal origin

From: Clinical analysis of Krukenberg tumours in patients with colorectal cancer—a review of 57 cases

  Number (N = 57) Percentage
Primary colorectal carcinoma
 Age at diagnosis of primary colorectal carcinoma
  <60 years 43 75.4
  ≥60 years 14 24.6
 Primary tumour site
  Sigmoid colon 19 33.3
  Rectum 11 19.3
  Ascending colon 9 15.8
  Caecum colon 8 14.0
  Transverse colon 5 8.8
  Descending colon 3 5.3
  Multiple sites 2 3.5
 Tumour histology
  Well differentiated 19 33.3
  Moderately differentiated 21 36.8
  Poorly differentiated 11 19.3
  Undifferentiated 6 10.5
 Depth of tumour invasion
  T3 21 36.8
  T4 36 63.2
 Primary lymph node metastasis
  Retroperitoneal lymph node metastasis 16 36.8
  Non-retroperitoneal lymph node metastasis 20 35.1
  None 21 28.1
Ovarian metastatic tumours
 Age at diagnosis of ovarian metastases
  <60 years 40 70.2
  ≥60 years 17 29.8
 Menses
  Pre-menopausal 32 56.1
  Post-menopausal 25 43.9
 Primary site
  Ovarian mass 18 31.6
  Abdominal pain 14 24.6
  Abdominal distension 11 19.3
  Incidentally discovered during operation 8 14.0
  Irregular vaginal bleeding 6 10.5
 Timing of ovarian metastasis
  Synchronous 21 36.8
  13–24 months 23 40.4
  >24 months 13 22.8
 Tumour size
  ≤10 cm 33 57.9
  >10 cm 24 42.1
 Ovarian involvement
  Unilateral 21 36.8
  Bilateral 36 63.2
 Extent of metastatic disease
   M ovary 28 49.1
  M1 14 24.6
  M2 15 26.3
 Extent of surgery
  Minimal 17 29.8
  Extensive 40 70.2
 Completeness of cytoreduction
  CC0 26 45.6
  CC1 16 28.1
  CC2 15 26.3
 Systemic chemotherapy
  Yes 34 59.6
  No 23 40.4
  1. Note: CC0 and CC1 are described as complete cytoreduction, CC2 as incomplete cytoreduction
  2. CC0 no macroscopic residual tumour, CC1 maximal diameter of residual tumour <2.5 mm, CC2 maximal diameter of residual tumour ≥2.5 mm, M ovary ovary-only metastasis, M1 metastasis confined to the pelvis, M2 metastasis beyond the pelvis