Table 1 Clinical features of 57 patients with KTs of colorectal origin
From: Clinical analysis of Krukenberg tumours in patients with colorectal cancer—a review of 57 cases
Number (N = 57) | Percentage | |
|---|---|---|
Primary colorectal carcinoma | ||
Age at diagnosis of primary colorectal carcinoma | ||
<60 years | 43 | 75.4 |
≥60 years | 14 | 24.6 |
Primary tumour site | ||
Sigmoid colon | 19 | 33.3 |
Rectum | 11 | 19.3 |
Ascending colon | 9 | 15.8 |
Caecum colon | 8 | 14.0 |
Transverse colon | 5 | 8.8 |
Descending colon | 3 | 5.3 |
Multiple sites | 2 | 3.5 |
Tumour histology | ||
Well differentiated | 19 | 33.3 |
Moderately differentiated | 21 | 36.8 |
Poorly differentiated | 11 | 19.3 |
Undifferentiated | 6 | 10.5 |
Depth of tumour invasion | ||
T3 | 21 | 36.8 |
T4 | 36 | 63.2 |
Primary lymph node metastasis | ||
Retroperitoneal lymph node metastasis | 16 | 36.8 |
Non-retroperitoneal lymph node metastasis | 20 | 35.1 |
None | 21 | 28.1 |
Ovarian metastatic tumours | ||
Age at diagnosis of ovarian metastases | ||
<60 years | 40 | 70.2 |
≥60 years | 17 | 29.8 |
Menses | ||
Pre-menopausal | 32 | 56.1 |
Post-menopausal | 25 | 43.9 |
Primary site | ||
Ovarian mass | 18 | 31.6 |
Abdominal pain | 14 | 24.6 |
Abdominal distension | 11 | 19.3 |
Incidentally discovered during operation | 8 | 14.0 |
Irregular vaginal bleeding | 6 | 10.5 |
Timing of ovarian metastasis | ||
Synchronous | 21 | 36.8 |
13–24 months | 23 | 40.4 |
>24 months | 13 | 22.8 |
Tumour size | ||
≤10 cm | 33 | 57.9 |
>10 cm | 24 | 42.1 |
Ovarian involvement | ||
Unilateral | 21 | 36.8 |
Bilateral | 36 | 63.2 |
Extent of metastatic disease | ||
M ovary | 28 | 49.1 |
M1 | 14 | 24.6 |
M2 | 15 | 26.3 |
Extent of surgery | ||
Minimal | 17 | 29.8 |
Extensive | 40 | 70.2 |
Completeness of cytoreduction | ||
CC0 | 26 | 45.6 |
CC1 | 16 | 28.1 |
CC2 | 15 | 26.3 |
Systemic chemotherapy | ||
Yes | 34 | 59.6 |
No | 23 | 40.4 |