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Table 2 Meta-analysis of IGFBP-3 expressions for esophageal cancer

From: The low IGFBP-3 level is associated with esophageal cancer patients: a meta-analysis

Groups

I 2

P a (heterogeneity)

OR

Lower limit

Upper limit

P b (OR)

Begg’s test

Egger’s test

Cancer risk

38.8%

0.179

2.342

1.655

3.313

0.000

0.734

0.434

3-year survival rate

71.20%

0.015

2.163*

1.092

4.287

0.027

0.734

0.814

Age

77.40%

0.035

0.980

0.520

1.860

0.733

1.000

Gender

4.70%

0.306

1.250

0.630

2.480

0.548

1.000

Location

0.00%

0.962

1.145

0.568

2.307

0.705

1.000

Tumor size

72.40%

0.057

1.650

0.900

3.010

0.536

1.000

T category

19.60%

0.265

2.870

1.510

5.450

0.005

1.000

N category

0.00%

0.863

3.211

1.561

6.607

0.002

1.000

M category

0.00%

0.380

3.270

1.670

6.400

0.001

1.000

TNM stage

0.00%

0.621

4.110

1.850

9.160

0.000

1.000

Survival status

0.00%

0.861

4.490

2.207

9.093

0.000

1.000

  1. * value of RR
  2. – unavailable
  3. aThe P value for heterogeneity
  4. bThe P value for OR