Table 1 Characteristics of studies included in the meta-analysis
From: The low IGFBP-3 level is associated with esophageal cancer patients: a meta-analysis
Study | Population | Case/control (n) | Treatment before studya | Test approaches of IGFBP-3 level | Cut-off value | Positivity rate | bResults 1 | Adjuvant therapy | Prognosis | cResults 2 |
|---|---|---|---|---|---|---|---|---|---|---|
Makoto Sohda (2004) [16] | Japan | 66/18 | No | ELISA | – | – | High | Surgery | Sur. Survival | No |
O. Yilmaz (2006) [21] | Turkey | 40/40 | No | ELISA | – | – | Low | – | – | – |
E. Di Martino (2006) [20] | UK | 39/38 | No | IHC/RT-PCR | 0 | 76.92% | High | Surgery | – | – |
Lei Zhao (2012) [15] | China | 110/56 | – | IHC | 4 | 51.82% | Low | – | Sur. Survival | High |
M. Natsuizaka (2014) [22] | Japan | 91/91 | – | IHC | 0 | 35.16% | Low | Surgery | Sur. Survival | low |
Li-Ling Luo (2015) [32] | China | 70/10 | Radiotherapy | IHC | 0.65 | 45.71% | High | Radiotherapy | Sur. Survival | High |
Peng Ye (2016) [23] | China | 264/132 | – | IHC | – | – | Low | – | – | – |