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Table 4 Subgroup analysis stratified by different stages

From: Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population

Genotype TNM staging
  Stage I ORa (95% CI) Stage II ORa (95%CI) Stage III ORa (95% CI) Stage IV ORa (95% CI)
−149C>T
TT 23 (9.8) 0.57 (0.32 1.78) 4 (2.2) 0.23 (0.29 1.57) 12 (5.0) 0.32 (0.31 1.58) 4 (13.3) 0.75 (0.31 1.28)
CT 78 (32.5) 0.92 (0.54 1.52) 41 (22.5) 0.38 (0.42 1.81) 68 (28.9) 0.65 (0.38 1.85) 10 (33.3) 1.02 (0.82 2.54)
CC 138 (57.7) Reference 136 (75.3) Reference 155 (66.1) Reference 15 (53.3) Reference
CT+TT 101 (42.3) 1.03 (0.68 1.55) 45 (24.7) 0.46 (0.28 0.77) 80 (32.9) 0.72 (0.47 1.10) 14 (46.6) 1.23 (0.44 3.46)
−2437T>A
AA 20 (8.1) 0.32 (0.28 1.35) 21 (11.8) 0.45 (0.28 2.51) 20 (8.3) 0.84 (0.81 1.95) 4 (13.3) 1.32 (0.82 1.69)
TA 91 (38.2) 0.72 (0.82 1.96) 66 (36.6) 0.78 (0.84 1.92) 101 (43.0) 0.97 (0.58 1.92) 15 (53.3) 1.56 (0.78 3.51)
TT 128 (53.7) Reference 93 (51.6) Reference 114 (48.7) Reference 10 (33.3) Reference
TA+AA 111 (46.3) 0.85 (0.57 1.27) 87 (48.4) 0.92 (0.59 1.44) 121 (51.3) 1.03 (0.69 1.55) 19 (66.6) 1.96 (0.66 5.84)
  1. OR odds ratio, CI confidence interval
  2. aAdjusted for age and sex in a logistic regression model