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Table 2 Genotype distribution of DNMT3B −149C>T and −2437T>A polymorphisms and their associations with lung cancer risk

From: Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population

Genotype No. of cases (%) No. of controlsa (%) ORb (95% CI) P value
−149C>T
TT 35 (5.1) 38 (6.3) 0.90 (0.62 2.37) 0.406
CT 249 (36.4) 172 (28.6) 1.42 (0.34 1.53) 0.541
CC 400 (58.5) 392 (65.1) Reference  
T-allele carriers 284 (41.5) 210 (34.9) 0.78 (0.57 1.05) 0.361
−2437T>A
AA 76 (11.1) 56 (9.3) 1.22 (0.58 1.35) 0.215
TA 269 (39.4) 241 (40.1) 1.00 (0.42 1.67) 0.308
TT 339 (49.5) 304 (50.6) Reference  
A-allele carriers 345 (50.5) 297 (49.4) 0.99 (0.74, 1.33) 0.167
  1. No. number of cases or controls, OR odds ratio, CI confidence interval
  2. aThe observed genotype distribution in controls was in accordance with the Hardy-Weinberg equilibrium (P = 0.153 for DNMT3B −149C>T and P = 0.187 for DNMT3B −2437T>A)
  3. bAdjusted for age and sex in a logistic regression model