Table 1 Baseline characteristics of subjects in lung cancer group and healthy control group case: 684; control: 602
From: Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population
No. of cases (%) | No. of controls (%) | Allele frequency | ||
|---|---|---|---|---|
χ 2 | P | |||
Gender | ||||
Male | 498 (72.8) | 400 (66.5) | 0.703 | 0.402 |
Female | 186 (28.2) | 202 (33.5) | ||
Age (x ± s) | 56.1 ± 11.3 | 57.1 ± 10.0 | 1.306 | 0.192 |
<60 | 408 (59.7) | 328 (54.5) | 2.006 | 0.157 |
≥60 | 276 (40.3) | 274 (45.5) | ||
Smoking status | ||||
Smokers | 458 (66.9) | 268 (44.6) | 37.461 | 0.001 |
Non-smokers | 226 (33.1) | 334 (55.4) | ||
Pathological type | ||||
SCC | 221 (32.3) | – | ||
AC | 257 (37.6) | – | ||
ASC | 64 (9.4) | – | ||
SCLC | 142 (20.8) | – | ||
TNM staging | ||||
I | 239 (34.9) | – | ||
II | 181 (26.5) | – | ||
III | 235 (34.4) | – | ||
IV | 29 (4.2) | – | ||
T2437A allele | ||||
T | 559 (69.2) | 497 (70.6) | 0.357 | 0.550 |
A | 249 (30.8) | 207 (29.4) | ||
C149T | ||||
C | 619 (76.6) | 559 (79.4) | 1.707 | 0.191 |
A | 189 (23.4) | 145 (20.6) | ||