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Table 1 Baseline characteristics of subjects in lung cancer group and healthy control group case: 684; control: 602

From: Associations of DNMT3B −149C>T and −2437T>A polymorphisms and lung cancer risk in Chinese population

  No. of cases (%) No. of controls (%) Allele frequency
χ 2 P
Gender
 Male 498 (72.8) 400 (66.5) 0.703 0.402
 Female 186 (28.2) 202 (33.5)
 Age (x ± s) 56.1 ± 11.3 57.1 ± 10.0 1.306 0.192
 <60 408 (59.7) 328 (54.5) 2.006 0.157
 ≥60 276 (40.3) 274 (45.5)
Smoking status
 Smokers 458 (66.9) 268 (44.6) 37.461 0.001
 Non-smokers 226 (33.1) 334 (55.4)
Pathological type
 SCC 221 (32.3)   
 AC 257 (37.6)   
 ASC 64 (9.4)   
 SCLC 142 (20.8)   
TNM staging
 I 239 (34.9)   
 II 181 (26.5)   
 III 235 (34.4)   
 IV 29 (4.2)   
T2437A allele
 T 559 (69.2) 497 (70.6) 0.357 0.550
 A 249 (30.8) 207 (29.4)
C149T
 C 619 (76.6) 559 (79.4) 1.707 0.191
 A 189 (23.4) 145 (20.6)
  1. SCC squamous cell carcinoma, AC adenomatous carcinoma, ASC adenosquamous carcinomas, SCLC small cell lung cancer, TNM tumor-node-metastasis