Table 1 Clinical and pathological characteristics of 88 patients and univariate analysis for OS
From: Prognostic value of p53 for colorectal cancer after surgical resection of pulmonary metastases
Factor | Number (%) | OS (months) | p value |
|---|---|---|---|
Age (years) | |||
≤60 | 61 (69.3) | 57.8 | 0.475 |
>60 | 27 (30.7) | 55.6 | |
Gender | |||
Male | 58 (65.9) | 57.8 | 0.729 |
Female | 30 (34.1) | 67.9 | |
Tumor size of lung metastasis (cm) | |||
≤3 | 75 (85.2) | 62.6 | 0.212 |
>3 | 13 (14.8) | 47.2 | |
Primary tumor localization | |||
Left-sided colon | 9 (10.2) | 41.2 | 0.185 |
Right-sided colon | 16 (18.2) | 67.9 | |
Rectum | 63 (71.6) | 61.6 | |
Metastases phase | |||
Synchronous metastases | 10 (11.4) | 46.1 | 0.661 |
Metachronous metastases | 78 (88.6) | 57.8 | |
Pulmonary metastases number | |||
Single | 71 (80.7) | 62.6 | 0.23 |
Multiple | 17 (19.3) | 49.8 | |
Extrapulmonary metastasis | |||
Yes | 5 (5.7) | 39.5 | 0.756 |
No | 83 (94.3) | 57.8 | |
Surgical procedures | |||
VATS | 59 (67.0) | 62.6 | 0.516 |
Thoracotomy | 29 (33.0) | 57.8 | |
Resection range | |||
Lung wedge resection | 52 (59.1) | 67.9 | 0.696 |
Pulmonary lobectomy | 36 (40.9) | 57.8 | |
Preoperative CEA level | |||
Normal | 64 (72.7) | 62.6 | 0.142 |
Elevated | 24 (27.3) | 42 | |
p53 IHC | |||
Positive | 42 (47.7) | 46.1 | 0.047 |
Negative | 46 (52.3) | 62.6 | |