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Table 1 Characteristic variable

From: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict chemotherapy outcomes and prognosis in patients with colorectal cancer and synchronous liver metastasis

Characteristics

Category

No. of patients (%)

Clinical background

 Sex

Male

35 (64)

Female

20 (36)

 Age (years)

<60

28 (51)

≥60

27 (49)

 Number of liver metastasis

≤3

27 (49)

>3

28 (51)

 Liver metastasis resection

No

43 (78)

Yes

12 (22)

 First-line chemotherapy

FOLFOX

21 (38)

XELOX

34 (62)

Surgical pathology

 Maximum size (cm)

≤4

29 (53)

>4

26 (47)

 Pathology

Adenocarcinoma

50 (91)

Mucinous or signet-ring carcinoma

5 (9)

 Differentiation

G1–G2

33 (60)

G3–G4

22 (40)

 Location

Colon

25 (45)

Rectum

30 (55)

 Tumor stage (T)

2

1 (2)

3

13 (24)

4

41 (74)

 Nodal status (N)

0

11 (20)

1

19 (35)

2

25 (45)

 Lymphovascular invasion

No

25 (45)

Yes

30 (55)

 Perineural invasion

No

28 (51)

Yes

27 (49)

 Extranodal tumor deposits

No

30 (55)

Yes

25 (45)

 MSI status

dMMR

4 (7)

pMMR

51 (93)

Blood biochemical test

 NLR

<4

41 (75)

≥4

14 (25)

 PLR

<150

31 (56)

≥150

24 (44)

 ALP

Normal

46 (84)

Elevated

9 (16)

 LDH

Normal

44 (80)

Elevated

11 (20)

 Serum CA199 level

Normal

20 (36)

Elevated

35 (64)

 Serum CEA level

Normal

12 (22)

Elevated

43 (78)