Table 2 The univariate and multivariate analysis of postoperative recurrence
From: The patterns and timing of recurrence after curative resection for gastric cancer in China
Clinical features | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
OR | 95% CI | p value | OR | 95% CI | p value | |
Age | ||||||
≦65 | ||||||
>65 | 1.178 | 0.916–1.514 | 0.201 | NA | NA | NA |
Sex | ||||||
Male | ||||||
Female | 0.837 | 0.648–1.080 | 0.171 | NA | NA | NA |
Hospital | ||||||
Specialist hospitals | ||||||
General hospitals | 1.915 | 1.529–2.398 | <0.001 | 1.632 | 1.238–2.151 | 0.001 |
Tumor location | ||||||
Non-GEJ | ||||||
GEJ | 1.683 | 1.319–2.146 | <0.001 | 1.431 | 1.066–1.922 | 0.017 |
AJCC stage | ||||||
I–II | ||||||
III | 2.608 | 2.070–3.286 | <0.001 | NA | NA | NA |
T stage | ||||||
T1–2 | ||||||
T3–4 | 2.861 | 2.188–3.741 | <0.001 | 2.332 | 1.675–3.245 | <0.001 |
N stage | ||||||
N0 | ||||||
N1–3 | 3.397 | 2.617–4.409 | <0.001 | 2.085 | 1.481–2.936 | <0.001 |
Positive LN ratio | ||||||
≦0.33 | ||||||
>0.33 | 3.577 | 2.759–4.638 | <0.001 | 2.283 | 1.656–3.145 | <0.001 |
No. of LN dissection | ||||||
<15 | ||||||
≧15 | 0.502 | 0.397–0.635 | <0.001 | NA | NA | NA |
Histological type | ||||||
Well-differentiated tumors | ||||||
Poorly differentiated tumors | 0.845 | 0.645–1.107 | 0.222 | 0.792 | 0.570–1.099 | 0.162 |
Signet ring cell cancer | 2.066 | 1.307–3.265 | 0.002 | 1.881 | 1.108–3.193 | 0.019 |
Lymphadenectomy extent | ||||||
D2 | ||||||
D0/D1 | 1.923 | 1.525–2.424 | <0.001 | 2.361 | 1.771–3.147 | <0.001 |
Neo-adjuvant chemotherapy | ||||||
Yes | ||||||
No | 1.260 | 0.756–2.100 | 0.374 | NA | NA | NA |
Adjuvant chemotherapy | ||||||
No | ||||||
Yes | 0.978 | 0.710–1.347 | 0.892 | NA | NA | NA |
Adjuvant chemotherapy regimen | ||||||
No | ||||||
Fluorouracil-based regimens | 0.947 | 0.687–1.306 | 0.740 | NA | NA | NA |
Other regimens | 2.414 | 1.096-5.315 | 0.029 | NA | NA | NA |
Adjuvant chemotherapy cycles | ||||||
No | ||||||
≦3 cycles | 0.754 | 0.527–1.080 | 0.123 | NA | NA | NA |
>3 cycles | 1.156 | 0.827–1.617 | 0.396 | NA | NA | NA |
Adjuvant radiotherapy | ||||||
Yes | ||||||
No | 2.152 | 0.980–4.725 | 0.056 | 3.868 | 1.493–10.022 | 0.005 |