Risks and benefits of combining denosumab and surgery in giant cell tumor of bone—a case series

Table 2 Treatment overview

Patient	Drug response	Surgical downstaging	Performed surgery	Filling after curettage	Local recurrence
1	Yes	Yes	Curettage + plate fixation	Cement	(Yes)
2	Yes	No	Curettage	Bone allograft	No
3	Yes	Yes	Curettage + plate fixation	Cement	No
4	Yes	No	Curettage	Cement	No
5	Yes	No	Curettage + plate fixation	Cement	No
6	Yes	No	Soft tissue excision	N/A	No
7	Yes	No	Curettage	Cement	Yes
8	Yes	Yes	Curettage	Cement + bone allograft	No
9	Yes	No	Curettage	Bone allograft	No
10	No	No	Resection and APC	N/A	No
11	Yes	Yes	Curettage	Bone allograft	No
12	Yes	Yes	Curettage + plate fixation	Cement	No
13	Yes	Yes	Curettage + plate fixation	Cement	No
14	Yes	Yes	Curettage	Bone allograft	No
15	No	No	Curettage + screw	Cement	No
16	Yes	No	Bone resection	N/A	No
17	No	No	Resection and APC	N/A	No
18	Yes	No	Bone resection	N/A	No
19	Yes	No	Bone resection	N/A	No
20	Yes	Yes	Curettage + plate fixation	Cement + bone allograft	No
21	Yes	Yes	Curettage	Bone allograft	No
22	Yes	No	Curettage + plate fixation	Cement	No
23	Yes	No	Curettage	Bone allograft	No
24	No	No	Curettage + plate fixation	Cement	No
25	Yes	Yes	Curettage	Bone allograft	No

ISSN: 1477-7819