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Table 4 Clinicopathological characteristics of the 12 patients in the validation set

From: The expression of microRNA 574-3p as a predictor of postoperative outcome in patients with esophageal squamous cell carcinoma

  Non-relapse Relapse p value
Case number 8 4  
Age (mean ± SD) 63.0 ± 10.3 66.7 ± 8.0 0.425
Gender
 Male 4 4 0.08
 Female 4 0  
Tumor location
 Upper/middle thoracic 5 2 0.67
 Lower thoracic 3 2  
Histological grade
 Well/moderate 7 2 0.16
 Poorly 1 2  
Pathologic tumor depth
 T1-2 2 1 1.00
 T3-4 6 3  
 Lymph node metastasis
 N0 3 1 0.66
 N1-3 5 3  
Distant metastasis
 M0 8 4 -
 M1 0 0  
TNM stage
 1–2 3 1 0.66
 3–4 5 3  
Lymphatic vessel invasion
 Negative 3 1 0.66
 Positive 5 3  
Venous invasion
 Negative 2 1 1.00
 Positive 6 3  
Curability
 R0 8 4
 R1 0 0  
 Preoperative chemotherapy 5 3
Preoperative CRT 0 0  
 Postoperative chemotherapy 2 3
 Postoperative CRT 0 0  
 Observation period (month, mean ± SD) 64.6 ± 18.3 51.1 ± 33.6 0.049
 Duration between surgery and tumor relapse 8.8 ± 2.9
Type of tumor relapse
 Liver (H) 0 2  
 Lymph node (Ly) 0 2  
 miR-574-3p (<0.7) 1 3 0.029
 miR-574-3p (≥0.7) 7 1  
 miR-106b (<1.00) 1 1 0.576
 miR-106b (≥1.00) 7 3  
 miR-1303 (<1.20) 5 2 0.576
 miR-1303 (≥1.20) 3 2