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Table 2 Main grade 3–4 toxicities of the included RCTs

From: Postoperative chemoradiotherapy versus chemotherapy for R0 resected gastric cancer with D2 lymph node dissection: an up-to-date meta-analysis

References Kwon et al. [14] Kim et al. [15] Zhu et al. [16] ARTIST 2012/2015
Characteristics CRT CT CRT CT CRT CT CRT CT
Patient number 31 30 46 44 186 165 230 228
Nausea/vomiting 2 (6.5) 4 (13.3) NR NR 8 (4.3) 0 35 (15.4) 36 (15.9)
Diarrhea 1 (3.2) 0 NR NR 3 (1.6) 0 2 (0.9) 5 (2.2)
Neutropenia 15 (48.4) 5 (16.7) NR NR 14 (7.5) 12 (7.3) 110 (48.4) 92 (40.7)
Anemia 4 (12.9) 5 (16.7) NR NR 0 0 1 (0.4) 4 (1.7)
Thrombocytopenia NR NR NR NR 0 0 2 (0.9) 0
Criteria NR NR CTCEA 3.0 CTCEA 2.0
  1. Numbers in the brackets refer to percentages
  2. CRT chemoradiotherapy, CT chemotherapy, NR not reported