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Table 4 Univariate survival analysis of OS and DFS in 120 patients with HCC

From: ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition

Characteristics

OS

DFS

HR

95 % CI

P

HR

95 % CI

P

Age (>50 vs ≤50 years)

1.397

0.898–2.175

0.138

1.418

0.931–2.161

0.104

Gender (male vs female)

0.737

0.414–1.311

0.299

0.874

0.521–1.466

0.610

Nodule (multiple vs single)

3.254

2.005–5.280

<0.001

3.204

2.003–5.125

<0.001

Tumor size (>5 vs ≤5 cm)

3.747

2.374–5.913

<0.001

3.949

2.531–6.161

<0.001

Capsule (poorly vs well)

1.048

0.677–1.623

0.832

1.119

0.737–1.697

0.598

Liver cirrhosis (without/mild vs moderate/severe)

8.984

5.443–14.827

<0.001

9.798

5.955–16.119

<0.001

TNM stage (III vs I/II)

13.612

7.240–25.589

<0.001

12.074

6.480–22.500

<0.001

Edmondson’s grade (III/IV vs I/II)

1.471

0.932–2.321

0.098

1.377

0.895–2.120

0.146

Child-Pugh class (B vs A)

1.056

0.625–1.785

0.839

1.125

0.689–1.838

0.638

Vascular invasion (present vs absent)

22.957

11.683–45.112

<0.001

19.039

10.248–35.372

<0.001

AFP (>400 vs ≤400 ng/ml)

0.983

0.634–1.523

0.939

0.983

0.648–1.492

0.936

HBsAg (positive vs negative)

0.887

0.457–1.721

0.722

0.919

0.489–1.729

0.793

ECM1 (positive vs negative)

3.066

1.691–5.562

<0.001

2.294

1.360–3.872

0.002

  1. P value was generated by univariate analyses using the Cox regression model. P < 0.05 was considered as statistically significant