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Table 4 Univariate survival analysis of OS and DFS in 120 patients with HCC

From: ECM1 promotes migration and invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition

Characteristics OS DFS
HR 95 % CI P HR 95 % CI P
Age (>50 vs ≤50 years) 1.397 0.898–2.175 0.138 1.418 0.931–2.161 0.104
Gender (male vs female) 0.737 0.414–1.311 0.299 0.874 0.521–1.466 0.610
Nodule (multiple vs single) 3.254 2.005–5.280 <0.001 3.204 2.003–5.125 <0.001
Tumor size (>5 vs ≤5 cm) 3.747 2.374–5.913 <0.001 3.949 2.531–6.161 <0.001
Capsule (poorly vs well) 1.048 0.677–1.623 0.832 1.119 0.737–1.697 0.598
Liver cirrhosis (without/mild vs moderate/severe) 8.984 5.443–14.827 <0.001 9.798 5.955–16.119 <0.001
TNM stage (III vs I/II) 13.612 7.240–25.589 <0.001 12.074 6.480–22.500 <0.001
Edmondson’s grade (III/IV vs I/II) 1.471 0.932–2.321 0.098 1.377 0.895–2.120 0.146
Child-Pugh class (B vs A) 1.056 0.625–1.785 0.839 1.125 0.689–1.838 0.638
Vascular invasion (present vs absent) 22.957 11.683–45.112 <0.001 19.039 10.248–35.372 <0.001
AFP (>400 vs ≤400 ng/ml) 0.983 0.634–1.523 0.939 0.983 0.648–1.492 0.936
HBsAg (positive vs negative) 0.887 0.457–1.721 0.722 0.919 0.489–1.729 0.793
ECM1 (positive vs negative) 3.066 1.691–5.562 <0.001 2.294 1.360–3.872 0.002
  1. P value was generated by univariate analyses using the Cox regression model. P < 0.05 was considered as statistically significant