The Diagnosis of Metastatic Axillary Lymph Nodes of Breast Cancer By Diffusion Weighted Imaging: a meta-analysis and systematic review

Table 1 Characteristics of inclusion articles

Author	Year	Nation	Design	No. of patients and nodes	b value (s/mm²)	Field strength (T)	ADC cutoff (×10⁻³mm/s²)	Mean ADC of metastases (×10⁻³mm/s²)	Mean ADC of benign (×10⁻³mm/s²)	Coil	Reference standard	tp	fp	fn	tn
Nakai	2011	Japan	NG	16, 216	0, 800	1.5	NG	1.04	1.22	Cardiac surface	Histopathologically	30	4	6	176
Kamitani	2012	Japan	Retro	108, 110	0, 1000	1.5	1.05	1.08	0.92	Body	Histopathologically	14	11	12	73
Fornasa	2013	Italy	Prosp	43, 43	0, 800	1.5	1.09	0.88	1.4	4-channel phased array	Histopathologically	18	2	1	22
He	2013	China	NG	136, 1242	500	1.5	1.68	1.37	1.77	8-channel phased array breast	Biopsy or surgical resection	138	498	4	602
He	2013	China	NG	136, 1242	800	1.5	1.35	1.18	1.55	8-channel phased array breast	Biopsy or surgical resection	134	376	8	724
Luo	2013	China	NG	36, 79	0, 800	1.5	0.889	0.79	1.04	8-channel phased array breast	Histopathologically	37	6	8	28
Chung	2013	South Korea	NG	110, 110	0, 1000	1.5 3.0	0.9	0.69	1.04	4-channel phased array breast	Histopathologically	68	26	22	136
Kim	2014	South Korea	Retro	252, 253	0, 750	1.5	0.986	0.91	1.27	Bilateral breast surface	Biopsy	69	26	22	136
Schipper	2014	Netherlands	Prosp	50, 135	0, 500 800	3.0	0.65	0.72	0.75	32-channel cardiac sensitivity encoding	Histopathologically	14	46	8	67
Yamaguchi	2014	Japan	NG	16, 52	0, 800	1.5	0.852	0.75	1.03	Breast	Biopsy	13	3	3	17
Razek	2015	Egypt	Prosp	34, 65	0, 500 1000	1.5	1.30	1.08	1.15	8-channel breast	Histopathologically	41	0	3	21

tp true positive, fp false positive, fn false negative, tn true negative, NG not given, Prosp prospective, Retro retrospective

ISSN: 1477-7819