Fig. 3

MPNST with NF-1 in a 47-year-old female. A well-defined, ovoid mass is located in the right pelvis wall, which demonstrates hypo-intensity on axial T1-weighted (C1) and obvious heterogeneous hyper-intensity on T2-weighted (C2) images. On enhanced T1 images (C3), there is strong enhancement in parts of the tumor with hypo-intense T2 signal, while moderate or slight enhancement in other parts. Note multiple subcutaneous neurofibromas. Hematoxylin-eosin staining result (100 times) (C4) shows prominence in nuclear mitosis activities and atypia