Table 6 Univariate and multivariate analyses of potential risk factors for distant metastasis in patients with invasive cancer (n = 272)

Age <40 years

1.5 (0.4–5.7)

0.51

1.2 (0.3–4.2)

0.78

T stage, T2 (vs. T1)

1

0.83

1

0.98

Positive LN

4.8 (1.3–17.7)

0.02*

3.4 (0.9–12.3)

0.04*

Stage, IIB–IIIA

3.1 (1.1–8.4)

0.03*

3.83 (1.4–10.8)

0.07

IBTR

11.5 (3.9–33.4)

<0.001*

14.4 (4.8–43.1)

<0.001*

Positive margin status

1

0.99

1

0.95

Omission of Radiotherapy

1

0.99

1

0.90

Negative ER

1.6 (0.5–4.4)

0.39

2.7 (0.1–10.6)

0.25

Negative PR

1.8 (0.6–4.9)

0.22

1.8 (0.7–4.8)

0.90

Positive HER2

1.2 (0.2–8.4)

0.92

1

0.98

Positive LVI

1.2 (1.0–10.1)

0.84

1

0.99

Positive Ki-67

1.1 (0.4–2.9)

0.87

1.2 (0.4–3.0)

0.65

High histologic grade

1

0.833

1

0.98