Table 2 Univariate and multivariate analyses of predictive risk factors for IBTR in DCIS (n = 50)
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (95 % CI) | p value | HR (95 % CI) | p value | |
Age <40 years | 2.0 (0.2–21.6) | 0.56 | 1.9 (0.2–17.8) | 0.54 |
Tumor size >2 cm | 1.1 (0.6–4.2) | 0.23 | 1.2 (0.1–5.3) | 0.29 |
Positive margin status | 4.7 (0.5–14.2) | 0.02* | 15.6 (2.7–66.3) | 0.007* |
Multiplicity | 2.5 (0.4–4.4) | 0.44 | 2.5 (0.2–2.5) | 0.42 |
High nuclear grade | 2 (0.1–9.1) | 0.63 | 1.2 (0.1–11.5) | 0.67 |
EIC positive | 1 | 0.99 | 1 | 0.99 |
Negative ER | 9.0 (1.2–65.6) | 0.03* | 6.7 (1.2–40.5) | 0.03* |
Negative PR | 10.5 (1.1–105.0) | 0.04* | 8.9 (0.9–79.4) | 0.05 |
Positive HER2 | 1 | 0.99 | 1 | 0.34 |
Comedo necrosis | 2.5 (0.1–16.3) | 0.40 | 2.2 (0.4–13.6) | 0.36 |
Omission of radiotherapy | 3.6 (0.5–25.8) | 0.19 | 3.4 (0.6–20.1) | 0.18 |