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Table 2 Univariate and multivariate analyses of predictive risk factors for IBTR in DCIS (n = 50)

From: Comparison of ipsilateral breast tumor recurrence after breast-conserving surgery between ductal carcinoma in situ and invasive breast cancer

Variables Univariate Multivariate
OR (95 % CI) p value HR (95 % CI) p value
Age <40 years 2.0 (0.2–21.6) 0.56 1.9 (0.2–17.8) 0.54
Tumor size >2 cm 1.1 (0.6–4.2) 0.23 1.2 (0.1–5.3) 0.29
Positive margin status 4.7 (0.5–14.2) 0.02* 15.6 (2.7–66.3) 0.007*
Multiplicity 2.5 (0.4–4.4) 0.44 2.5 (0.2–2.5) 0.42
High nuclear grade 2 (0.1–9.1) 0.63 1.2 (0.1–11.5) 0.67
EIC positive 1 0.99 1 0.99
Negative ER 9.0 (1.2–65.6) 0.03* 6.7 (1.2–40.5) 0.03*
Negative PR 10.5 (1.1–105.0) 0.04* 8.9 (0.9–79.4) 0.05
Positive HER2 1 0.99 1 0.34
Comedo necrosis 2.5 (0.1–16.3) 0.40 2.2 (0.4–13.6) 0.36
Omission of radiotherapy 3.6 (0.5–25.8) 0.19 3.4 (0.6–20.1) 0.18
  1. *p < 0.05