Skip to main content

Table 5 Parameters correlated with PFS and/or OS in 30 adult UTGs

From: Clinical, radiological, and pathological features of 33 adult unilateral thalamic gliomas

Characteristics Median PFS (INR)a Progression-free survival rates (%) P value Median OS (INR)a Overall survival rates (%) P value
6 months 12 months 18 months 24 months 6 months 12 months 18 months 24 months
Age (years)             
 <42 N/A 87.5 62.5 25.0 6.3 <0.001 N/A 100.0 93.8 56.3 18.8 <0.001
 ≥42 N/A 64.3 50.0 28.6 14.3 N/A 71.4 64.3 35.7 35.7
Sex             
 Male N/A 78.9 47.4 31.6 10.5 0.037 N/A 94.7 84.2 57.9 36.8 <0.001
 Female N/A 72.7 72.7 18.2 9.1 N/A 72.7 72.7 27.3 9.1
Lateral             
 Left N/A 84.6 69.2 30.8 15.4 <0.001 N/A 92.3 92.3 46.2 38.5 <0.001
 Right N/A 70.6 47.1 23.5 5.9 N/A 82.4 70.6 47.1 17.6
Preoperative kps             
 ≥60 N/A 85.7 66.7 33.3 14.3 <0.001 N/A 95.2 90.5 52.3 23.8 <0.001
 <60 9(3–20) 55.6 33.3 11.1 0.0 N/A 66.7 55.6 33.3 33.3
Postoperative kps             
 ≥60 N/A 84.0 72.0 36.0 16.0 <0.001 N/A 92.0 84.0 52.0 40.0 <0.001
 <60 N/A 40.0 20.0 0.0 0.0 N/A 60.0 60.0 20.0 20.0
Symptom duration (months)             
 ≥2 N/A 93.3 73.3 40.0 20.0 <0.001 N/A 93.3 93.3 66.7 46.7 <0.001
 <2 11(2–24) 60.0 40.0 13.3 0.0 N/A 80.0 66.7 26.7 6.7
Cystic changes             
 Yes N/A 85.7 71.4 42.9 28.6 <0.001 N/A 100.0 100.0 85.7 57.1 <0.001
 No N/A 73.9 52.2 21.7 4.3 N/A 82.6 73.9 34.8 17.4
Diameter (cm)             
 <3.9 N/A 91.7 66.7 41.7 16.7 <0.001 N/A 91.7 91.7 50.0 33.3 <0.001
 ≥3.9 N/A 66.7 50.0 16.7 5.5 N/A 83.3 72.2 44.4 22.2
Pathology             
 Low grade N/A 100.0 100.0 50.0 25.0 <0.001 N/A 100.0 100.0 75.0 50.0 <0.001
 High grade N/A 68.2 40.9 18.2 4.5 N/A 81.8 72.7 36.4 18.2
Postoperative v-p shunt             
 Yes 14.5(12–24) 100.0 75.0 25.0 0.0 N/A 100.0 100.0 50.0 25.0 <0.001
 No N/A 73.1 53.8 26.9 11.5 N/A 84.6 76.9 46.2 26.9
Resection             
 Gtr N/A 82.4 64.7 35.3 17.6 <0.001 N/A 88.2 76.5 52.9 35.3 <0.001
 Str/pr 12(2–20) 69.2 46.2 15.4 0.0 N/A 84.6 84.6 38.5 15.4
  1. N/A not available
  2. aMedian PFS and median OS was calculated based on the final status of follow-up
  3. bMeans no correlation in univariate analysis