Table 2 Prognostic factors of overall survival and disease-free survival

 Male sex

1.092

0.741–1.609

0.653

0.975

0.716–1.328

0.873

 Age >60 years

0.848

0.633–1.135

0.263

0.934

0.737–1.185

0.572

 ECOG (0/1/2)

0.681

0.426–1.112

0.752

0.704

0.421–1.191

0.726

 Child-Pugh A/B

3.123

0.995–9.800

0.099

1.780

0.570–5.560

0.364

 HBV (+)

1.050

0.754–1.463

0.772

1.140

0.863–1.505

0.350

 HCV (+)

1.142

0.695–1.876

0.608

1.174

0.773–1.782

0.462

 AST >40 U/L

1.592

1.209–2.096

0.001

1.528

1.217–1.919

<0.001

 ALT >40 U/L

1.142

0.866–1.506

0.348

1.192

0.949–1.496

0.133

 TBIL >17.5 μmol/L

0.789

0.584–1.066

0.117

0.854

0.671–1.086

0.194

 ALB ≤35 g/L

1.154

0.628–2.119

0.651

1.422

0.859–2.353

0.239

 PT >14 s

2.012

1.064–3.803

0.052

2.191

0.780–3.753

0.401

 AFP >400 ng/mL

1.516

1.118–2.057

0.009

1.434

1.113–1.847

0.007

 Liver cirrhosis (+)

0.890

0.658–1.204

0.450

1.030

0.798–1.329

0.821

 Tumor size >5 cm

2.925

2.212–3.867

<0.001

1.904

1.518–2.388

<0.001

 Microscopic portal vein (+)

2.281

1.714–3.035

<0.001

1.825

1.432–2.325

<0.001

 Macroscopic vascular invasion (+)

2.819

1.963–4.048

<0.001

2.228

1.616–3.082

<0.001

 Multiple nodes but ≤3

2.818

1.975–4.058

<0.001

2.486

1.823–3.390

<0.001

 Blood loss >1000 mL

1.649

1.049–2.591

0.042

1.032

0.618–1.641

0.327

 Blood transfusion (+)

3.310

2.402–4.561

<0.001

1.229

0.712–1.548

0.614

 Complications (+)

1.254

0.937–1.679

0.133

1.439

1.130–1.832

0.003

 Major liver resection

2.475

1.854–3.258

<0.001

1.941

1.528–2.465

<0.001

 Adjuvant TAC/TACE

1.132

0.683–2.126

0.627

0.134

0.512–1.168

0.079

 AST >40 U/L

1.044

0.722–1.510

0.818

0.860

0.611–1.209

0.385

 AFP >400 ng/mL

1.523

1.107–2.095

0.010

1.213

0.922–1.598

0.168

 Tumor size >5 cm

2.002

1.443–2.778

<0.001

1.489

1.129–2.078

0.013

 Microscopic portal vein (+)

1.559

1.126–2.159

0.007

1.266

0.967–1.657

0.086

 Macroscopic vascular invasion (+)

1.655

1.096–2.499

0.017

0.982

0.672–1.435

0.926

 Multiple nodes but ≤3

2.134

1.460–3.120

<0.001

0.888

0.636–1.239

0.484

 Blood loss >1000 mL

1.142

0.708–1.842

0.585

1.073

0.696–1.654

0.749

 Blood transfusion

1.025

0.686–1.531

0.904

1.238

0.945–1.621

0.121

 Major liver resection

1.348

0.964–1.887

0.081

1.100

0.836–1.449

0.495

 Complications

1.136

0.877–1.472

0.333