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Table 1 Clinicopathologic background according to the disease status

From: Extended resection including adjacent organs and Ki-67 labeling index are prognostic factors in patients with retroperitoneal soft tissue sarcomas

Variables

All (n = 23)

Simple resection (n = 9)

Extended resection (n = 14)

P value

Median age, years (IQR)

62 (51.5–71)

62 (42–70)

62 (52.5–71)

0.68a

Sex, n (%)

   

0.57b

 Men

15 (65 %)

7 (78 %)

8 (57 %)

 

 Women

8 (35 %)

2 (22 %)

6 (43 %)

 

Follow-up, months (IQR)

30 (18–51.5)

19 (18–33)

30.5 (24–87.5)

0.12a

Tumor size, mm (IQR)

77 (50–210)

80 (50–120)

75 (51–112)

0.99a

Symptoms positive, n (%)

   

0.87b

 Yes

12 (52 %)

4 (44 %)

8 (57 %)

 

 No

11 (48 %)

5 (56 %)

6 (43 %)

 

Infiltration into the adjacent organs, n (%)

   

0.01*,b

 Yes

11 (48 %)

1 (11 %)

10 (71 %)

 

 No

12 (52 %)

8 (89 %)

4 (29 %)

 

Margins, n (%)

   

0.94b

 R0

4 (17 %)

2 (22 %)

2 (14 %)

 

 R1

17 (74 %)

6 (67 %)

11 (79 %)

 

 R2

2 (9 %)

1 (11 %)

1 (7 %)

 

Histological type, n (%)

   

0.87b

 Liposarcoma

12 (52 %)

4 (44 %)

8 (57 %)

 

 Leiomyosarcoma

4 (17 %)

2 (22 %)

2 (14 %)

 

 MFH

3 (14 %)

1 (11 %)

2 (14 %)

 

 Other

4 (17 %)

2 (22 %)

2 (14 %)

 

Tumor grade, n (%)

   

0.82b

 Grade 1

3 (14 %)

1 (11 %)

2 (14 %)

 

 Grade 2

4 (17 %)

2 (22 %)

2 (14 %)

 

 Grade 3

16 (69 %)

6 (67 %)

10 (71 %)

 

Necrosis, n (%)

   

0.88b

 Yes

17 (74 %)

7 (78 %)

10 (71 %)

 

 No

6 (26 %)

2 (22 %)

4 (29 %)

 

Mitosis, n (%)

   

0.61b

 1–9/10HPF

14 (61 %)

5 (56 %)

9 (64 %)

 

 10–20/HPF

9 (39 %)

4 (44 %)

5 (36 %)

 

Ki-67 LI, n (%)

   

0.42b

 <25 %

13 (56 %)

4 (44 %)

9 (64 %)

 

 ≥25 %

10 (44 %)

5 (56 %)

5 (36 %)

 
  1. Simple resection: resection of only the tumor; extended resection: resection extended to adjacent organs; tumor grade: using the French Federation of Cancer Centers Sarcoma Group grading system
  2. IQR interquartile range, R0 microscopically negative margin, R1 microscopically positive margin, R2 gross residual margin, MFH malignant fibrous histiocytoma, HPF high-power field, Ki-67 LI Ki-67 labeling index
  3. aMann-Whitney test
  4. bFisher’s exact test or chi-square with Yates’ correction
  5. * = P <0.05